Entresto and Cefixime drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Entresto (sacubitril; valsartan) and Cefixime (cefixime). Common drug interactions include eosinophilia among females and cellulitis among males.

The phase IV clinical study analyzes what interactions people have when they take Entresto and Cefixime. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Entresto?

Entresto has active ingredients of sacubitril; valsartan. eHealthMe is studying from 126,628 Entresto users. Check the latest studies of Entresto.

What is Cefixime?

Cefixime has active ingredients of cefixime. eHealthMe is studying from 3,237 Cefixime users. Check the latest studies of Cefixime.

On Jul, 17, 2026

11 people who take Entresto and Cefixime together, and have interactions are studied.

Entresto and Cefixime drug interactions.

What are the common drug interactions of Entresto and Cefixime, by gender? *:

female:

Eosinophilia (eosinophil count in the peripheral blood exceeds)
Death

male:

Cellulitis (infection under the skin)
Cellulitis gangrenous (localized inflammation of the soft or connective tissue with considerable mass of body tissue dies (necrosis))
Subcutaneous abscess
Unresponsive to stimuli
Urinary tract infection
Wound abscess (pus in wound)
Metastatic squamous cell carcinoma (cancer of squamous cells spreads to other part)
Acute respiratory failure
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Cardiac arrest

What are the common drug interactions of Entresto and Cefixime, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cellulitis (infection under the skin)
Cellulitis gangrenous (localized inflammation of the soft or connective tissue with considerable mass of body tissue dies (necrosis))
Genital abscess (build up of pus in genital)
Groin abscess (pus in groin)
Pelvic abscess
Perineal abscess
Scrotal abscess (pus in scrotum)
Scrotal gangrene (death of scrotum cells)
Sepsis (a severe blood infection that can lead to organ failure and death)
Septic shock (shock due to blood infection)

40-49:

Encephalopathy (functioning of the brain is affected by some agent or condition)
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)

50-59:

n/a

60+:

Eosinophilia (eosinophil count in the peripheral blood exceeds)
Unresponsive to stimuli
Metastatic squamous cell carcinoma (cancer of squamous cells spreads to other part)
Cardiac arrest
Death
Dizziness
Pruritus (severe itching of the skin)
Pulseless electrical activity
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

What are the existing conditions these people have? *

Acute Coronary Syndrome (acute chest pain and other symptoms that happen because the heart does not get blood): 3 people, 27.27%
Hypotension (abnormally low blood pressure): 2 people, 18.18%
Cardiac Failure: 2 people, 18.18%
Type 2 Diabetes: 2 people, 18.18%
Weight Decreased: 2 people, 18.18%
Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 1 person, 9.09%
Lower Respiratory Tract Infection: 1 person, 9.09%
Neuralgia (pain in one or more nerves): 1 person, 9.09%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 1 person, 9.09%
Pain: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Entresto and Cefixime?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously