Entresto and Gentamicin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Entresto (sacubitril; valsartan) and Gentamicin (gentamicin sulfate). Common drug interactions include headache among females and weight decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Entresto and Gentamicin. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Entresto?

Entresto has active ingredients of sacubitril; valsartan. eHealthMe is studying from 126,628 Entresto users. Check the latest studies of Entresto.

What is Gentamicin?

Gentamicin has active ingredients of gentamicin sulfate. It is often used in urinary tract infection. eHealthMe is studying from 21,654 Gentamicin users. Check the latest studies of Gentamicin.

On Jul, 11, 2026

26 people who take Entresto and Gentamicin together, and have interactions are studied.

Entresto and Gentamicin drug interactions.

What are the common drug interactions of Entresto and Gentamicin, by gender? *:

female:

Headache (pain in head)
Fall
Back pain
Blood pressure increased
Peripheral swelling
Urinary tract infection bacterial
Limb injury
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Ear infection
Eye infection

male:

Weight decreased
Death
Haemoglobin decreased
Joint swelling
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Platelet count decreased
Pyrexia (fever)
Sepsis (a severe blood infection that can lead to organ failure and death)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Dizziness postural

What are the common drug interactions of Entresto and Gentamicin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Pain
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

50-59:

Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)

60+:

Arthralgia (joint pain)
Back pain
Peripheral swelling
Upper limb fracture
Blood urine present
Death
Renal haemorrhage (bleeding from kidney)
Blood pressure decreased
Body temperature increased
Chills (felling of cold)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 12 people, 46.15%
High Blood Pressure: 3 people, 11.54%
Cardiac Failure: 3 people, 11.54%
Endocarditis (inflammation in heart muscle): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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