Entresto and Pulmicort drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Entresto (sacubitril; valsartan) and Pulmicort (budesonide). Common drug interactions include dyspnoea among females and pollakiuria among males.

The phase IV clinical study analyzes what interactions people have when they take Entresto and Pulmicort. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Entresto?

Entresto has active ingredients of sacubitril; valsartan. eHealthMe is studying from 126,628 Entresto users. Check the latest studies of Entresto.

What is Pulmicort?

Pulmicort has active ingredients of budesonide. It is often used in asthma. eHealthMe is studying from 34,980 Pulmicort users. Check the latest studies of Pulmicort.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

28 people who take Entresto and Pulmicort together, and have interactions are studied.

Entresto and Pulmicort drug interactions.

What are the common drug interactions of Entresto and Pulmicort, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Pneumonia
Death
Anaemia (lack of blood)
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Cardiomyopathy (weakening of the heart muscle)
Chronic left ventricular failure (long lasting functional impairment of left ventricle of heart)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Fatigue (feeling of tiredness)
Hypertransaminasaemia

male:

Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Weight decreased
Renal impairment (severely reduced kidney function)
Sinus node dysfunction (a group of abnormal heart rhythms)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Ventricular extrasystoles (premature cardiac contraction)
Abdominal pain
Abdominal wall haematoma (abdominal wall blood clotting)
Anaemia (lack of blood)
C-reactive protein increased

What are the common drug interactions of Entresto and Pulmicort, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

50-59:

n/a

60+:

Chronic left ventricular failure (long lasting functional impairment of left ventricle of heart)
Anaemia (lack of blood)
Hypertransaminasaemia
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Myalgia (muscle pain)
Pneumonia
Productive cough
Somnolence (a state of near-sleep, a strong desire for sleep)
Weight decreased
Cardiac failure congestive

What are the existing conditions these people have? *

Cardiac Failure: 6 people, 21.43%
Cardiac Failure Chronic: 3 people, 10.71%
Wheezing (a high-pitched whistling sound made while you breath): 2 people, 7.14%
Pain: 2 people, 7.14%
Ischaemic Cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease): 2 people, 7.14%
Dyspnea (difficult or laboured breathing): 2 people, 7.14%
Cystic Fibrosis (disease of the secretary glands): 2 people, 7.14%
Congestive Cardiomyopathy (weakening of heart muscle): 2 people, 7.14%
Cardiac Disorder: 2 people, 7.14%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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