Epinephrine and Welchol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Epinephrine (epinephrine) and Welchol (colesevelam hydrochloride). Common drug interactions include osteomyelitis among females and gastrointestinal disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Epinephrine and Welchol. It is created by eHealthMe based on reports of 66 people who take the same drugs from the FDA, and is updated regularly.

What is Epinephrine?

Epinephrine has active ingredients of epinephrine. It is often used in asthma. eHealthMe is studying from 21,290 Epinephrine users. Check the latest studies of Epinephrine.

What is Welchol?

Welchol has active ingredients of colesevelam hydrochloride. It is often used in high blood cholesterol. eHealthMe is studying from 11,309 Welchol users. Check the latest studies of Welchol.



On Jul, 28, 2026

66 people who take Epinephrine and Welchol together, and have interactions are studied.

Epinephrine and Welchol drug interactions.

What are the common drug interactions of Epinephrine and Welchol, by gender? *:

female:

  1. Osteomyelitis (infection of bone)
  2. Wheezing (a high-pitched whistling sound made while you breath)
  3. Anxiety
  4. Ear pain
  5. Eating disorder
  6. Hypoaesthesia (reduced sense of touch or sensation)
  7. Hypoxia (low oxygen in tissues)
  8. Infusion site pruritus (severe itching at infusion site)
  9. Infusion site swelling
  10. Neuralgia (pain in one or more nerves)

male:

  1. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  2. Abdominal distension
  3. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  4. Infusion site bruising
  5. Infusion site extravasation (flow of (blood or lymph) from infusion site)
  6. Infusion site haemorrhage (bleeding from infusion site)
  7. Infusion site mass
  8. Infusion site swelling
  9. Infusion site vesicles (fluid- or air-filled cavity or sac at infusion site)
  10. Insomnia (sleeplessness)

What are the common drug interactions of Epinephrine and Welchol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
  2. Fall
  3. Headache (pain in head)
  4. Viral infection
  5. Loss of consciousness
  6. Pain
  7. Oropharyngeal pain
  8. Abdominal pain upper
  9. Anaemia (lack of blood)
  10. Blood glucose decreased

40-49:

  1. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)

50-59:

  1. Weight decreased
  2. Bartonellosis (infectious disease produced by bacteria of the genus bartonella)
  3. Ear infection
  4. Epstein-barr virus infection
  5. Heart rate increased
  6. Infection
  7. Localised infection (infection at the single location)
  8. Lyme disease (a bacterial infection that is spread to humans by infected ticks)
  9. Sinusitis (inflammation of sinus)
  10. Urinary tract infection

60+:

  1. Sinusitis (inflammation of sinus)
  2. Colitis (inflammation of colon)
  3. Ear infection
  4. Hypersensitivity
  5. Infusion site pruritus (severe itching at infusion site)
  6. Multiple allergies (allergy to multiple agents)
  7. Nausea (feeling of having an urge to vomit)
  8. Nephrolithiasis (calculi in the kidneys)
  9. Pneumonia
  10. Respiratory tract infection

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 33 people, 50.00%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 9 people, 13.64%
  3. Sinusitis (inflammation of sinus): 8 people, 12.12%
  4. Primary Immunodeficiency Syndrome: 8 people, 12.12%
  5. Immunodeficiency: 8 people, 12.12%
  6. Weight Decreased: 6 people, 9.09%
  7. Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 6 people, 9.09%
  8. Otitis (ear infection): 6 people, 9.09%
  9. Headache (pain in head): 6 people, 9.09%
  10. Combined Immunodeficiency: 5 people, 7.58%

* Approximation only. Some reports may have incomplete information.

Do you take Epinephrine and Welchol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Epinephrine and Welchol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Epinephrine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Welchol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Epinephrine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Welchol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on epinephrine and colesevelam hydrochloride (the active ingredients of Epinephrine and Welchol, respectively), and Epinephrine and Welchol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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