Epipen and Medroxyprogesterone acetate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Epipen (epinephrine) and Medroxyprogesterone acetate (medroxyprogesterone acetate). Common drug interactions include pain among females.

The phase IV clinical study analyzes what interactions people have when they take Epipen and Medroxyprogesterone acetate. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Epipen?

Epipen has active ingredients of epinephrine. It is often used in anaphylaxis. eHealthMe is studying from 23,760 Epipen users. Check the latest studies of Epipen.

What is Medroxyprogesterone acetate?

Medroxyprogesterone acetate has active ingredients of medroxyprogesterone acetate. It is often used in birth control. eHealthMe is studying from 12,600 Medroxyprogesterone acetate users. Check the latest studies of Medroxyprogesterone acetate.



On Jul, 15, 2026

11 people who take Epipen and Medroxyprogesterone acetate together, and have interactions are studied.

Epipen and Medroxyprogesterone acetate drug interactions.

What are the common drug interactions of Epipen and Medroxyprogesterone Acetate, by gender? *:

female:

  1. Pain
  2. Allergy to animal
  3. Dyspnoea (difficult or laboured respiration)
  4. Fatigue (feeling of tiredness)
  5. Gait disturbance
  6. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  7. Haemoglobin increased
  8. Headache (pain in head)
  9. Heart rate increased
  10. Hypersensitivity

male:

n/a

What are the common drug interactions of Epipen and Medroxyprogesterone Acetate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Acne (skin problems that cause pimples)
  2. Breast tenderness
  3. Depression
  4. Intermenstrual bleeding
  5. Mood swings (an extreme or rapid change in mood)
  6. Suicidal ideation
  7. Swelling
  8. Syncope (loss of consciousness with an inability to maintain postural tone)

20-29:

n/a

30-39:

  1. Blood pressure systolic increased
  2. Chest discomfort
  3. Dysphonia (speech disorder attributable to a disorder of phonation)
  4. Dyspnoea (difficult or laboured respiration)
  5. Fatigue (feeling of tiredness)
  6. Gait disturbance
  7. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  8. Haemoglobin increased
  9. Headache (pain in head)
  10. Heart rate increased

40-49:

  1. Depression

50-59:

  1. Sinusitis (inflammation of sinus)

60+:

  1. Chronic kidney disease

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 36.36%
  2. Asthma: 2 people, 18.18%
  3. Vulvovaginal Mycotic Infection (vulvovaginal fungal infection): 1 person, 9.09%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 9.09%
  5. Fever: 1 person, 9.09%
  6. Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 9.09%
  7. Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 9.09%
  8. Food Allergy: 1 person, 9.09%
  9. Fungal Infection: 1 person, 9.09%
  10. Gastric Ph Decreased: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Epipen and Medroxyprogesterone acetate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Epipen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Medroxyprogesterone acetate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Epipen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Medroxyprogesterone acetate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on epinephrine and medroxyprogesterone acetate (the active ingredients of Epipen and Medroxyprogesterone acetate, respectively), and Epipen and Medroxyprogesterone acetate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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