Epitol and Norco drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Epitol (carbamazepine) and Norco (acetaminophen; hydrocodone bitartrate). Common drug interactions include dizziness among females and urticaria among males.

The phase IV clinical study analyzes what interactions people have when they take Epitol and Norco. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Epitol?

Epitol has active ingredients of carbamazepine. It is often used in bipolar disorder. eHealthMe is studying from 397 Epitol users. Check the latest studies of Epitol.

What is Norco?

Norco has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 74,063 Norco users. Check the latest studies of Norco.

On Aug, 12, 2026

23 people who take Epitol and Norco together, and have interactions are studied.

What are the common drug interactions of Epitol and Norco, by gender? *:

female:

Dizziness
Hypoaesthesia (reduced sense of touch or sensation)
Ankle brachial index decreased
Antinuclear antibody increased
Anxiety
Asthenia (weakness)
Double stranded dna antibody positive
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Herpes zoster
Insomnia (sleeplessness)

male:

Urticaria (rash of round, red welts on the skin that itch intensely)
Dyspnoea (difficult or laboured respiration)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest discomfort
Chest pain
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Cough
Depression
Diplopia (double vision)
Dizziness

What are the common drug interactions of Epitol and Norco, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Urticaria (rash of round, red welts on the skin that itch intensely)
Dyspnoea (difficult or laboured respiration)
Pruritus (severe itching of the skin)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaphylactic reaction (serious allergic reaction)
Arthralgia (joint pain)
Balance disorder
Blindness transient (sudden loss of vision)
Burning sensation
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

50-59:

Dizziness
Insomnia (sleeplessness)
Intermittent claudication
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Pain in extremity
Peripheral ischaemia (impaired circulation to an extremity)
Skin discolouration (change of skin colour)
Vertigo cns origin
Vision blurred
Visual impairment

60+:

Gait disturbance

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 17 people, 73.91%
Neuralgia (pain in one or more nerves): 15 people, 65.22%
Fabry's Disease (build up of a particular type of fat, called globotriaosylceramide, in the body's cells): 3 people, 13.04%
Nausea (feeling of having an urge to vomit): 2 people, 8.70%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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