Colace and Brain hypoxia - a phase IV clinical study of FDA data

Summary:

Brain hypoxia is reported as a side effect among people who take Colace (docusate ), especially for people who are female, 60+ old, also take Fish Oil, and have Primary immunodeficiency syndrome.

The phase IV clinical study analyzes which people have Brain hypoxia when taking Colace. It is created by eHealthMe based on reports of 41,100 people who have side effects when taking Colace from the FDA, and is updated regularly.

What is Colace?

Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.

What is Brain hypoxia?

Brain hypoxia (reduced supply of oxygen to the brain) is found to be associated with 192 drugs and 333 conditions by eHealthMe. Check the latest studies of Brain hypoxia.



On Aug, 12, 2026

41,100 people reported to have side effects when taking Colace.
Among them, 14 people (0.03%) have Brain hypoxia.

Could Colace cause Brain hypoxia?

Among these 14 people:

What is the gender of people who have Brain hypoxia when taking Colace? *

  • female: 57.14 %
  • male: 42.86 %

What is the age of people who have Brain hypoxia when taking Colace? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 18.18 %
  • 50-59: 0.0 %
  • 60+: 81.82 %

What are other drugs people take besides Colace? *

  1. Claritin: 6 people, 42.86%
  2. Vitamin D3: 6 people, 42.86%
  3. Fish Oil: 6 people, 42.86%
  4. Zyrtec: 5 people, 35.71%
  5. Flonase: 5 people, 35.71%
  6. Melatonin: 5 people, 35.71%
  7. Zantac: 5 people, 35.71%
  8. Magnesium Gluconate: 5 people, 35.71%
  9. Magnesium: 4 people, 28.57%
  10. Lisinopril: 4 people, 28.57%

What are other side effects people have besides Brain hypoxia? *

  1. Pneumonia: 9 people, 64.29%
  2. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 7 people, 50.00%
  3. Skin Wrinkling (wrinkle on skin): 5 people, 35.71%
  4. Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 5 people, 35.71%
  5. Rashes (redness): 5 people, 35.71%
  6. Nasopharyngitis (inflammation of the nasopharynx): 5 people, 35.71%
  7. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 5 people, 35.71%
  8. Feeling Abnormal: 5 people, 35.71%
  9. Atypical Pneumonia (acute respiratory disease marked by high fever and coughing): 5 people, 35.71%
  10. Haemolytic Anaemia (anaemia due to haemolysis): 5 people, 35.71%

What are the existing conditions these people have? *

  1. Primary Immunodeficiency Syndrome: 5 people, 35.71%
  2. Immunodeficiency Common Variable: 4 people, 28.57%
  3. Thrombolysis (resolving the blood clot): 3 people, 21.43%
  4. Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 7.14%
  5. Renal Cell Carcinoma (a kidney cancer): 1 person, 7.14%
  6. Pain: 1 person, 7.14%
  7. Nerve Injury: 1 person, 7.14%
  8. Heart Rate Increased: 1 person, 7.14%
  9. Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 7.14%
  10. Endometrial Cancer: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Colace and have Brain hypoxia?

- Check whether Brain hypoxia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Colace:

Brain hypoxia treatments and more:

How severe was Brain hypoxia and when was it recovered:

Expand to all the drugs that have ingredients of docusate :

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Colace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Brain hypoxia:

Browse all the conditions that are associated with Brain hypoxia:


How the study uses the data?

The study uses data from the FDA. It is based on docusate (the active ingredients of Colace) and Colace (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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