Keflex and Xopenex hfa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Keflex (cephalexin) and Xopenex hfa (levalbuterol tartrate). Common drug interactions include fatigue among females and osteoarthritis among males.

The phase IV clinical study analyzes what interactions people have when they take Keflex and Xopenex hfa. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Keflex?

Keflex has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 15,844 Keflex users. Check the latest studies of Keflex.

What is Xopenex hfa?

Xopenex hfa has active ingredients of levalbuterol tartrate. It is often used in asthma. eHealthMe is studying from 2,529 Xopenex hfa users. Check the latest studies of Xopenex hfa.



On Aug, 12, 2026

14 people who take Keflex and Xopenex hfa together, and have interactions are studied.

Keflex and Xopenex hfa drug interactions.

What are the common drug interactions of Keflex and Xopenex Hfa, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Headache (pain in head)
  3. Nausea (feeling of having an urge to vomit)
  4. Abdominal pain upper
  5. Constipation
  6. Death
  7. Dyspnoea (difficult or laboured respiration)
  8. Influenza
  9. Abdominal distension
  10. Abdominal pain

male:

  1. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  2. Cor pulmonale chronic (long lasting enlargement of the right ventricle of the heart)
  3. Rosacea (a skin condition that causes facial redness)
  4. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  5. Testicular failure (testicles cannot produce sperm or male hormones)
  6. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  7. Anxiety
  8. Blood creatinine increased
  9. Chronic kidney disease
  10. Depression

What are the common drug interactions of Keflex and Xopenex Hfa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Blood creatinine increased
  4. Chronic kidney disease
  5. Depression
  6. Emotional distress
  7. Hydronephrosis (water inside the kidney)
  8. Nephrolithiasis (calculi in the kidneys)
  9. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  10. Pain

60+:

  1. Rosacea (a skin condition that causes facial redness)
  2. Cor pulmonale chronic (long lasting enlargement of the right ventricle of the heart)
  3. Restless legs syndrome (a powerful urge to move your legs)
  4. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  5. Testicular failure (testicles cannot produce sperm or male hormones)
  6. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  7. Ear infection
  8. Flatulence (flatus expelled through the anus)
  9. Ill-defined disorder
  10. Influenza

What are the existing conditions these people have? *

  1. Herpes Zoster: 4 people, 28.57%
  2. Indigestion: 3 people, 21.43%
  3. Wheezing (a high-pitched whistling sound made while you breath): 2 people, 14.29%
  4. Muscle Spasms (muscle contraction): 2 people, 14.29%
  5. Nausea (feeling of having an urge to vomit): 2 people, 14.29%
  6. Nausea And Vomiting: 2 people, 14.29%
  7. Pain: 2 people, 14.29%
  8. Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 14.29%
  9. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 1 person, 7.14%
  10. Dry Eyes (lack of adequate tears): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Keflex and Xopenex hfa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Keflex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Xopenex hfa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Keflex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xopenex hfa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on cephalexin and levalbuterol tartrate (the active ingredients of Keflex and Xopenex hfa, respectively), and Keflex and Xopenex hfa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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