Eprex and Soliris drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Eprex (epoetin alfa) and Soliris (eculizumab). Common drug interactions include blood pressure increased among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Eprex and Soliris. It is created by eHealthMe based on reports of 96 people who take the same drugs from the FDA, and is updated regularly.

What is Eprex?

Eprex has active ingredients of epoetin alfa. eHealthMe is studying from 5,554 Eprex users. Check the latest studies of Eprex.

What is Soliris?

Soliris has active ingredients of eculizumab. It is often used in paroxysmal nocturnal hemoglobinuria (pnh). eHealthMe is studying from 58,821 Soliris users. Check the latest studies of Soliris.

On Jul, 18, 2026

96 people who take Eprex and Soliris together, and have interactions are studied.

What are the common drug interactions of Eprex and Soliris, by gender? *:

female:

Blood pressure increased
Malaise (a feeling of general discomfort or uneasiness)
Dyspnoea exertional (breathlessness or shortness of breath)
Nasopharyngitis (inflammation of the nasopharynx)
Lethargy (tiredness)
Pyrexia (fever)
Asthenia (weakness)
Haemorrhage (bleeding)
Dizziness
Platelet count decreased

male:

Fatigue (feeling of tiredness)
Haemoglobin decreased
Nasopharyngitis (inflammation of the nasopharynx)
Arthralgia (joint pain)
Pain in extremity
Vomiting
Blood iron increased
Influenza like illness
Night sweats (sweating in night)
Pain

What are the common drug interactions of Eprex and Soliris, by age (0-1 to 60+)? *:

0-1:

Chronic kidney disease
Hypertension (high blood pressure)
Infection

2-9:

Candidiasis (candidiasis or thrush is a fungal infection)
Device related infection
Hypertension (high blood pressure)
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Pulmonary hypertension (increase in blood pressure in the lung artery)

10-19:

n/a

20-29:

Pharyngitis (inflammation of the pharynx, causing a sore throat)
Pneumonia

30-39:

Arthralgia (joint pain)
Pain in extremity
Vomiting
Dizziness
Back pain
Nephrolithiasis (calculi in the kidneys)
Balance disorder
Blood pressure fluctuation
Blood pressure increased
Cough

40-49:

n/a

50-59:

Dyspnoea exertional (breathlessness or shortness of breath)
Fatigue (feeling of tiredness)
Haemoglobin decreased
Influenza like illness
Lethargy (tiredness)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Nasopharyngitis (inflammation of the nasopharynx)
Night sweats (sweating in night)
Pain
Pain in extremity

60+:

Fatigue (feeling of tiredness)
Dyspnoea (difficult or laboured respiration)
Back pain
Cough
Lower respiratory tract infection
Anaemia (lack of blood)
Contusion (a type of hematoma of tissue in which capillaries)
Platelet count decreased
Nasopharyngitis (inflammation of the nasopharynx)
Oropharyngeal pain

What are the existing conditions these people have? *

Anaemia (lack of blood): 48 people, 50.00%
Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 36 people, 37.50%
High Blood Pressure: 11 people, 11.46%
Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 7 people, 7.29%
Pain: 5 people, 5.21%

* Approximation only. Some reports may have incomplete information.

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