Erbitux and Ellence drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Erbitux (cetuximab) and Ellence (epirubicin hydrochloride). Common drug interactions include neutrophil count decreased among females and blood potassium decreased among males.
The phase IV clinical study analyzes what interactions people have when they take Erbitux and Ellence. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Erbitux?
Erbitux has active ingredients of cetuximab. It is often used in cancer. eHealthMe is studying from 19,276 Erbitux users. Check the latest studies of Erbitux.
What is Ellence?
Ellence has active ingredients of epirubicin hydrochloride. eHealthMe is studying from 943 Ellence users. Check the latest studies of Ellence.
12 people who take Erbitux and Ellence together, and have interactions are studied.

What are the common drug interactions of Erbitux and Ellence, by gender? *:
female:
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- Febrile neutropenia (fever with reduced white blood cells)
- Hyperkalaemia (damage to or disease of the kidney)
- Infusion related reaction
male:
- Blood potassium decreased
- Blood pressure immeasurable
- Febrile neutropenia (fever with reduced white blood cells)
- Malignant neoplasm progression (cancer tumour came back)
- Neuropathy peripheral (surface nerve damage)
- Neutropenia (an abnormally low number of neutrophils)
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- Oesophageal adenocarcinoma metastatic (a cancer tumour of an epithelium in oesophagus spreads to other parts)
- Pulmonary embolism (blockage of the main artery of the lung)
- Rash
What are the common drug interactions of Erbitux and Ellence, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Drug hypersensitivity
- Dyspnoea (difficult or laboured respiration)
- Malignant neoplasm progression (cancer tumour came back)
- Neuropathy peripheral (surface nerve damage)
- Oesophageal adenocarcinoma metastatic (a cancer tumour of an epithelium in oesophagus spreads to other parts)
- Rash
- Respiratory failure (inadequate gas exchange by the respiratory system)
40-49:
n/a
50-59:
- Pulmonary embolism (blockage of the main artery of the lung)
- Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
- Unresponsive to stimuli
- Blood pressure immeasurable
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Infusion related reaction
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
60+:
- Blood potassium decreased
- Caecitis (inflammation of the cecum)
- Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
- Dehydration (dryness resulting from the removal of water)
- Neutropenia (an abnormally low number of neutrophils)
- Renal failure (kidney dysfunction)
* Approximation only. Some reports may have incomplete information.
Do you take Erbitux and Ellence?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Erbitux and Ellence:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Erbitux:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ellence:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Erbitux and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ellence and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Gupta D, Shukla P, Bisht SS, Bhatt ML, Pant MC, Srivastava K, "Deep vein and artery thrombosis associated with cetuximab-based chemoradiotherapy", Indian journal of pharmacology, 2011 Jan .
- Gupta D, Shukla P, Bisht SS, Bhatt ML, Pant MC, Srivastava K, "Deep vein and artery thrombosis associated with cetuximab-based chemoradiotherapy", Indian journal of pharmacology, 2011 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on cetuximab and epirubicin hydrochloride (the active ingredients of Erbitux and Ellence, respectively), and Erbitux and Ellence (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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