Erbitux and Tagamet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Erbitux (cetuximab) and Tagamet (cimetidine). Common drug interactions include diarrhoea among females and dermatitis acneiform among males.

The phase IV clinical study analyzes what interactions people have when they take Erbitux and Tagamet. It is created by eHealthMe based on reports of 56 people who take the same drugs from the FDA, and is updated regularly.

What is Erbitux?

Erbitux has active ingredients of cetuximab. It is often used in cancer. eHealthMe is studying from 19,276 Erbitux users. Check the latest studies of Erbitux.

What is Tagamet?

Tagamet has active ingredients of cimetidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 9,011 Tagamet users. Check the latest studies of Tagamet.



On Jul, 12, 2026

56 people who take Erbitux and Tagamet together, and have interactions are studied.

Erbitux and Tagamet drug interactions.

What are the common drug interactions of Erbitux and Tagamet, by gender? *:

female:

  1. Diarrhoea
  2. Dizziness
  3. Weight decreased
  4. Hirsutism (abnormal growth of hair on a person's face and body, esp. on a woman)
  5. Abdominal pain lower
  6. Anaemia (lack of blood)
  7. Anaphylactic reaction (serious allergic reaction)
  8. Arthralgia (joint pain)
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  10. Bone pain

male:

  1. Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
  2. Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
  3. Flushing (the warm, red condition of human skin)
  4. Ileus (a painful obstruction of the ileum or other part of the intestine)
  5. Pruritus (severe itching of the skin)
  6. White blood cell count decreased
  7. Back pain
  8. Blood pressure decreased
  9. Chest pain
  10. Dyspnoea (difficult or laboured respiration)

What are the common drug interactions of Erbitux and Tagamet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Infusion related reaction

40-49:

  1. Infusion related reaction

50-59:

  1. Blood pressure decreased
  2. Erythema (redness of the skin)
  3. Flushing (the warm, red condition of human skin)
  4. Hirsutism (abnormal growth of hair on a person's face and body, esp. on a woman)
  5. Hypotension (abnormally low blood pressure)
  6. Mucosal inflammation (infection of mucous membrane)
  7. Urticaria (rash of round, red welts on the skin that itch intensely)
  8. Anaphylactic reaction (serious allergic reaction)
  9. Back pain
  10. Cardiac failure congestive

60+:

  1. Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
  2. Fatigue (feeling of tiredness)
  3. Erythema (redness of the skin)
  4. Headache (pain in head)
  5. Insomnia (sleeplessness)
  6. Pain
  7. Rash
  8. Sinusitis (inflammation of sinus)
  9. Chest discomfort
  10. Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

  1. Colon Cancer: 19 people, 33.93%
  2. Oral Cancer (mouth cancer): 7 people, 12.50%
  3. Colon Cancer Metastatic (cancer of colon spreads to other part of body): 6 people, 10.71%
  4. Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 4 people, 7.14%
  5. Pain: 3 people, 5.36%
  6. High Blood Pressure: 3 people, 5.36%

* Approximation only. Some reports may have incomplete information.

Do you take Erbitux and Tagamet?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Erbitux and Tagamet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Erbitux:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tagamet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Erbitux and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tagamet and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on cetuximab and cimetidine (the active ingredients of Erbitux and Tagamet, respectively), and Erbitux and Tagamet (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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