Erythromycin and Mevacor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Erythromycin (erythromycin) and Mevacor (lovastatin). Common drug interactions include hyperkalaemia among females and abdominal distension among males.

The phase IV clinical study analyzes what interactions people have when they take Erythromycin and Mevacor. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Erythromycin?

Erythromycin has active ingredients of erythromycin. It is often used in acne. eHealthMe is studying from 12,563 Erythromycin users. Check the latest studies of Erythromycin.

What is Mevacor?

Mevacor has active ingredients of lovastatin. It is often used in high blood cholesterol. eHealthMe is studying from 4,988 Mevacor users. Check the latest studies of Mevacor.



On Jul, 16, 2026

18 people who take Erythromycin and Mevacor together, and have interactions are studied.

Erythromycin and Mevacor drug interactions.

What are the common drug interactions of Erythromycin and Mevacor, by gender? *:

female:

  1. Hyperkalaemia (damage to or disease of the kidney)
  2. Hypervolaemia (abnormally increased volume of blood)
  3. Hypoaesthesia (reduced sense of touch or sensation)
  4. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  5. Hypotension (abnormally low blood pressure)
  6. Hypovolaemia (a decreased volume of circulating blood in the body)
  7. Insomnia (sleeplessness)
  8. Loss of consciousness
  9. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
  10. Malaise (a feeling of general discomfort or uneasiness)

male:

  1. Abdominal distension
  2. Anion gap increased
  3. Pancreatitis (inflammation of pancreas)
  4. Renal failure acute (rapid kidney dysfunction)
  5. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  6. Sepsis (a severe blood infection that can lead to organ failure and death)
  7. Vomiting
  8. Blood creatinine increased
  9. Blood urea increased
  10. Cardiac index increased

What are the common drug interactions of Erythromycin and Mevacor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Difficulty in walking
  2. Fibromyalgia syndrome (constant pain in their muscles and soft tissues)
  3. Muscle weakness (a lack of muscle strength)

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Hepatocellular damage (liver damage)
  2. Hypoaesthesia (reduced sense of touch or sensation)
  3. Nerve injury
  4. Pain
  5. Peripheral neuropathy (damage to nerves of the peripheral nervous system)
  6. Personality change
  7. Pulmonary embolism (blockage of the main artery of the lung)
  8. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  9. Road traffic accident
  10. Ulcer

50-59:

n/a

60+:

  1. Chronic kidney disease
  2. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  3. Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
  4. Livedo reticularis (a lace-like purplish discoloration of the skin)
  5. Multi-organ failure (multisystem organ failure)
  6. Muscle weakness (a lack of muscle strength)
  7. Oliguria (not enough urine)
  8. Pancreatitis (inflammation of pancreas)
  9. Renal failure acute (rapid kidney dysfunction)
  10. Sepsis (a severe blood infection that can lead to organ failure and death)

What are the existing conditions these people have? *

  1. Renal Injury (kidney injury): 3 people, 16.67%
  2. Pain: 3 people, 16.67%
  3. Infection: 3 people, 16.67%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 16.67%
  5. Cardiac Disorder: 3 people, 16.67%
  6. Menopause (end of monthly cycles in women): 2 people, 11.11%
  7. High Blood Pressure: 2 people, 11.11%
  8. Blood Pressure Abnormal: 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Erythromycin and Mevacor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Erythromycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Mevacor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Erythromycin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mevacor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on erythromycin and lovastatin (the active ingredients of Erythromycin and Mevacor, respectively), and Erythromycin and Mevacor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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