Esbriet and Centrum silver drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Esbriet (pirfenidone) and Centrum silver (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e). Common drug interactions include hospitalisation among females and ageusia among males.

The phase IV clinical study analyzes what interactions people have when they take Esbriet and Centrum silver. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Esbriet?

Esbriet has active ingredients of pirfenidone. eHealthMe is studying from 39,858 Esbriet users. Check the latest studies of Esbriet.

What is Centrum silver?

Centrum silver has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 19,997 Centrum silver users. Check the latest studies of Centrum silver.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

13 people who take Esbriet and Centrum silver together, and have interactions are studied.

Esbriet and Centrum silver drug interactions.

What are the common drug interactions of Esbriet and Centrum Silver, by gender? *:

female:

Hospitalisation
Nausea (feeling of having an urge to vomit)
Pericardial effusion (fluid around the heart)
Rash
Urticaria (rash of round, red welts on the skin that itch intensely)
Vomiting
Death
Dizziness
Pruritus (severe itching of the skin)
Diarrhoea

male:

Ageusia (loss of taste functions of the tongue)
Death
Decreased appetite
Epistaxis (bleed from the nose)
Erectile dysfunction

What are the common drug interactions of Esbriet and Centrum Silver, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Ageusia (loss of taste functions of the tongue)
Death
Urticaria (rash of round, red welts on the skin that itch intensely)
Vomiting
Decreased appetite
Diarrhoea
Drug hypersensitivity
Erectile dysfunction
Hospitalisation
Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

Idiopathic Pulmonary Fibrosis (chronic lung disease): 12 people, 92.31%

* Approximation only. Some reports may have incomplete information.

Do you take Esbriet and Centrum silver?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously