Escitalopram oxalate and Metolazone drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Escitalopram oxalate (escitalopram oxalate) and Metolazone (metolazone). Common drug interactions include confusional state among females and dehydration among males.
The phase IV clinical study analyzes what interactions people have when they take Escitalopram oxalate and Metolazone. It is created by eHealthMe based on reports of 61 people who take the same drugs from the FDA, and is updated regularly.
What is Escitalopram oxalate?
Escitalopram oxalate has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 17,930 Escitalopram oxalate users. Check the latest studies of Escitalopram oxalate.
What is Metolazone?
Metolazone has active ingredients of metolazone. It is often used in swelling. eHealthMe is studying from 13,411 Metolazone users. Check the latest studies of Metolazone.
61 people who take Escitalopram oxalate and Metolazone together, and have interactions are studied.

What are the common drug interactions of Escitalopram Oxalate and Metolazone, by gender? *:
female:
- Confusional state
- Delirium (wild excitement)
- Depressed mood
- Disturbance in attention
- Dizziness
- Drug ineffective
- Dysphagia (a condition in which swallowing is difficult or painful)
- Epistaxis (bleed from the nose)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Glossitis (infection of tongue with soreness)
male:
- Dehydration (dryness resulting from the removal of water)
- Dyspnoea (difficult or laboured respiration)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Death
- Decreased appetite
- Diarrhoea
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
- Enteritis (inflammation of the small intestine)
- Fatigue (feeling of tiredness)
- General physical health deterioration (weak health status)
What are the common drug interactions of Escitalopram Oxalate and Metolazone, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Right ventricular failure (right half of the heart fails to work)
- Abdominal pain
- Arthralgia (joint pain)
- Back pain
- Blood bilirubin increased
- Cardiac arrest
- Disease progression
- Dyspnoea exertional (breathlessness or shortness of breath)
50-59:
- Pulse absent
- Retching (strong involuntary effort to vomit)
- Ventricular fibrillation (abnormally irregular heart rhythm)
- Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
- Abdominal pain upper
- Anaphylactic reaction (serious allergic reaction)
- Blood glucose increased
- Cardiac failure
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
60+:
- Urinary tract infection
- Pneumonia
- Infection
- Oxygen saturation decreased
- Anaemia (lack of blood)
- Anuria (failure of the kidneys to produce urine)
- Cardiac arrest
- Contusion (a type of hematoma of tissue in which capillaries)
- Multi-organ failure (multisystem organ failure)
- Renal failure chronic (long lasting kidney dysfunction)
What are the existing conditions these people have? *
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 8 people, 13.11%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 9.84%
- Multiple Myeloma (cancer of the plasma cells): 5 people, 8.20%
- Immunodeficiency Common Variable: 5 people, 8.20%
- Stress And Anxiety: 4 people, 6.56%
- Pain: 4 people, 6.56%
* Approximation only. Some reports may have incomplete information.
Do you take Escitalopram oxalate and Metolazone?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Escitalopram oxalate (17,930 reports)
- Metolazone (13,411 reports)
Browse all drug interactions of Escitalopram oxalate and Metolazone:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Escitalopram oxalate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Metolazone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Escitalopram oxalate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Metolazone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on escitalopram oxalate and metolazone (the active ingredients of Escitalopram oxalate and Metolazone, respectively), and Escitalopram oxalate and Metolazone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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