Escitalopram and Esidrix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Escitalopram (escitalopram oxalate) and Esidrix (hydrochlorothiazide). Common drug interactions include somnolence among females and electrocardiogram qt prolonged among males.

The phase IV clinical study analyzes what interactions people have when they take Escitalopram and Esidrix. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Escitalopram?

Escitalopram has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 78,080 Escitalopram users. Check the latest studies of Escitalopram.

What is Esidrix?

Esidrix has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 1,846 Esidrix users. Check the latest studies of Esidrix.

On Jul, 26, 2026

26 people who take Escitalopram and Esidrix together, and have interactions are studied.

Escitalopram and Esidrix drug interactions.

What are the common drug interactions of Escitalopram and Esidrix, by gender? *:

female:

Somnolence (a state of near-sleep, a strong desire for sleep)
Constipation
Haematuria (presence of blood in urine)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Leukocytoclastic vasculitis (inflammation of small blood vessels (usually post-capillary venules in the dermis), characterized by palpable purpura)
Overdose
Balance disorder
Clostridium test positive
Confusional state
Dyspnoea (difficult or laboured respiration)

male:

Electrocardiogram qt prolonged
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Sinusitis (inflammation of sinus)
Supraventricular extrasystoles (premature electrical impulse in the heart, generated above the level of the ventricle)
Troponin increased
Ventricular extrasystoles (premature cardiac contraction)
Agitation (state of anxiety or nervous excitement)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Atrioventricular block first degree (heart block first degree)

What are the common drug interactions of Escitalopram and Esidrix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Haematoma (collection of blood outside the blood vessels)
Pyrexia (fever)

50-59:

Balance disorder
Confusional state
Somnolence (a state of near-sleep, a strong desire for sleep)
Sinusitis (inflammation of sinus)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Gamma-glutamyltransferase increased
Hepatitis cholestatic (flow of bile from the liver is slowed or blocked)
Renal failure acute (rapid kidney dysfunction)

60+:

Constipation
Haematuria (presence of blood in urine)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Cardiac disorder
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Dehydration (dryness resulting from the removal of water)
Dental caries
Depressed level of consciousness
Dry mouth
Dysphonia (speech disorder attributable to a disorder of phonation)

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 11.54%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 7.69%
Polymyalgia Rheumatica (pain in many muscles): 2 people, 7.69%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 7.69%
Embolism Venous (embolus may pass into the arterial system): 2 people, 7.69%
Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 2 people, 7.69%
Chronic Renal Failure (kidney failure): 2 people, 7.69%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 7.69%
Asthma: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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