Estazolam and Oxycontin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Estazolam (estazolam) and Oxycontin (oxycodone hydrochloride). Common drug interactions include constipation among females and cardiac failure among males.
The phase IV clinical study analyzes what interactions people have when they take Estazolam and Oxycontin. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.
What is Estazolam?
Estazolam has active ingredients of estazolam. It is often used in insomnia. eHealthMe is studying from 2,758 Estazolam users. Check the latest studies of Estazolam.
What is Oxycontin?
Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 212,533 Oxycontin users. Check the latest studies of Oxycontin.
34 people who take Estazolam and Oxycontin together, and have interactions are studied.

What are the common drug interactions of Estazolam and Oxycontin, by gender? *:
female:
- Constipation
- Depression
- Drug dependence
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Haemangioma of liver (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in liver)
- Post procedural complication
- Pulmonary granuloma (tiny lump of inflamed tissue in the lungs)
- Rash macular (small, flat red spots)
- Tenosynovitis (inflammation of the fluid-filled sheath (called the synovium) that surrounds a tendon)
- Wound infection
male:
- Cardiac failure
- Death
- Malaise (a feeling of general discomfort or uneasiness)
- Pancreatic carcinoma (pancreatic cancer)
- Pneumonia cytomegaloviral (cmv pneumonia is caused by a member of a group of herpes-type viruses)
- Skin erosion (a discontinuity of the skin)
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
What are the common drug interactions of Estazolam and Oxycontin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Asphyxia (a condition in which there is an extreme decrease in the concentration of oxygen in the body)
- Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
- Substance abuse
40-49:
- Bone disorder
- Dental caries
- Gingival swelling (gums swelling)
- Hyperhidrosis (abnormally increased sweating)
- Jaw disorder (jaw disease)
- Tooth abscess (pus formation in tooth)
- Tooth extraction
- Toothache (tooth pain)
- Abdominal discomfort
- Accident
50-59:
- Atelectasis (partial or complete collapse of the lung)
- Ileus (a painful obstruction of the ileum or other part of the intestine)
- Constipation
- Depression
- Drug dependence
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Haemangioma of liver (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in liver)
- Post procedural complication
- Pulmonary granuloma (tiny lump of inflamed tissue in the lungs)
- Rash macular (small, flat red spots)
60+:
- Cardiac failure
- Apnoea (suspension of external breathing)
- Death
- Drug ineffective
- Dysgeusia (disorder of the sense of taste)
- Pneumonia cytomegaloviral (cmv pneumonia is caused by a member of a group of herpes-type viruses)
- Skin erosion (a discontinuity of the skin)
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
What are the existing conditions these people have? *
- Lung Cancer - Non-Small Cell (lung cancer): 11 people, 32.35%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 17.65%
- Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 6 people, 17.65%
- Fever: 3 people, 8.82%
- Dyspnea (difficult or laboured breathing): 3 people, 8.82%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 8.82%
- Constipation: 3 people, 8.82%
- Asthma: 3 people, 8.82%
- Blood Potassium Decreased: 3 people, 8.82%
- Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 8.82%
* Approximation only. Some reports may have incomplete information.
Do you take Estazolam and Oxycontin?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Estazolam and Oxycontin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Estazolam:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Oxycontin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Estazolam and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Oxycontin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on estazolam and oxycodone hydrochloride (the active ingredients of Estazolam and Oxycontin, respectively), and Estazolam and Oxycontin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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