Estrace and Bydureon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Estrace (estradiol) and Bydureon (exenatide synthetic). Common drug interactions include injection site pain among females.

The phase IV clinical study analyzes what interactions people have when they take Estrace and Bydureon. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Estrace?

Estrace has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 16,703 Estrace users. Check the latest studies of Estrace.

What is Bydureon?

Bydureon has active ingredients of exenatide synthetic. It is often used in type 2 diabetes. eHealthMe is studying from 24,309 Bydureon users. Check the latest studies of Bydureon.

On Jul, 15, 2026

15 people who take Estrace and Bydureon together, and have interactions are studied.

What are the common drug interactions of Estrace and Bydureon, by gender? *:

female:

Injection site pain
Injection site pruritus (severe itching at injection site)
Feeling cold
Hunger
Hypoaesthesia (reduced sense of touch or sensation)
Injection site extravasation (flow of (blood or lymph) from injection site)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Rash
Rash pruritic (redness with itching)
Sneezing

male:

n/a

What are the common drug interactions of Estrace and Bydureon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Blood glucose increased
Injection site pain
Injection site pruritus (severe itching at injection site)
Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)
Drug ineffective
Early satiety (feeling full before completing a normal sized meal)
Feeling cold
Hunger
Hypoaesthesia (reduced sense of touch or sensation)

50-59:

Chronic kidney disease
Injection site erythema (redness at injection site)
Injection site haemorrhage (bleeding from injection site)
Injection site pain
Injection site pruritus (severe itching at injection site)
Injection site reaction
Injection site swelling
Injection site urticaria (rash of round, red welts on the skin at injection site)
Pancreatic carcinoma metastatic (pancreatic cancer- metastatic)
Renal failure (kidney dysfunction)

60+:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Vaginal haemorrhage (vaginal bleeding)
Injection site erythema (redness at injection site)
Injection site irritation
Injection site nodule (small swelling or aggregation of cells in the body, esp. an abnormal one at injection site)
Injection site pain
Injection site pruritus (severe itching at injection site)
Nephrogenic anaemia (anaemia due to kidney disease)
Pancreatic carcinoma (pancreatic cancer)

What are the existing conditions these people have? *

High Blood Cholesterol: 4 people, 26.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 26.67%
High Blood Pressure: 2 people, 13.33%
Stress And Anxiety: 2 people, 13.33%
Multiple Allergies (allergy to multiple agents): 2 people, 13.33%
Migraine (headache): 2 people, 13.33%
Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 13.33%
Diabetes: 2 people, 13.33%
Depression: 2 people, 13.33%
Rashes (redness): 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

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