Ketoconazole and Sciatica - a phase IV clinical study of FDA data

Summary:

Sciatica is reported as a side effect among people who take Ketoconazole (ketoconazole), especially for people who are male, 60+ old, also take Ibuprofen, and have Narcolepsy.

The phase IV clinical study analyzes which people have Sciatica when taking Ketoconazole. It is created by eHealthMe based on reports of 15,751 people who have side effects when taking Ketoconazole from the FDA, and is updated regularly.

What is Ketoconazole?

Ketoconazole has active ingredients of ketoconazole. It is often used in fungal infection. eHealthMe is studying from 16,014 Ketoconazole users. Check the latest studies of Ketoconazole.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,136 drugs and 1,433 conditions by eHealthMe. Check the latest studies of Sciatica.



On Jul, 15, 2026

15,751 people reported to have side effects when taking Ketoconazole.
Among them, 27 people (0.17%) have Sciatica.

Could Ketoconazole cause Sciatica?

Among these 27 people:

What is the gender of people who have Sciatica when taking Ketoconazole? *

  • female: 39.13 %
  • male: 60.87 %

What is the age of people who have Sciatica when taking Ketoconazole? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 33.33 %
  • 50-59: 33.33 %
  • 60+: 33.33 %

What are other drugs people take besides Ketoconazole? *

  1. Ibuprofen: 9 people, 33.33%
  2. Adderall: 7 people, 25.93%
  3. Norco: 7 people, 25.93%
  4. Xanax: 6 people, 22.22%
  5. Zyrtec: 5 people, 18.52%
  6. Prednisone: 5 people, 18.52%
  7. Vitamin C: 5 people, 18.52%
  8. Fish Oil: 5 people, 18.52%
  9. Wellbutrin: 5 people, 18.52%
  10. Xyrem: 5 people, 18.52%

What are other side effects people have besides Sciatica? *

  1. High Blood Cholesterol: 8 people, 29.63%
  2. Pain: 8 people, 29.63%
  3. Hypoaesthesia (reduced sense of touch or sensation): 7 people, 25.93%
  4. Chest Pain: 7 people, 25.93%
  5. Back Pain: 7 people, 25.93%
  6. Pain In Extremity: 7 people, 25.93%
  7. Weight Decreased: 6 people, 22.22%
  8. Oedema (fluid collection in tissue): 6 people, 22.22%
  9. Osteoporosis (bones weak and more likely to break): 6 people, 22.22%
  10. Anhedonia (inability to experience pleasure from activities usually found enjoyable): 6 people, 22.22%

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 18.52%
  2. Pain: 4 people, 14.81%
  3. Prostate Cancer: 3 people, 11.11%
  4. Multiple Myeloma (cancer of the plasma cells): 3 people, 11.11%
  5. Hiv Infection: 2 people, 7.41%
  6. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 7.41%
  7. Multifocal Motor Neuropathy (a progressively worsening condition where muscles in the extremities gradually weaken): 2 people, 7.41%
  8. Cough: 2 people, 7.41%
  9. Parkinson's Disease: 2 people, 7.41%
  10. Drowsiness: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Ketoconazole and have Sciatica?

- Check whether Sciatica is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ketoconazole:

Sciatica treatments and more:

How severe was Sciatica and when was it recovered:

Expand to all the drugs that have ingredients of ketoconazole:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ketoconazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica:

Browse all the conditions that are associated with Sciatica:


How the study uses the data?

The study uses data from the FDA. It is based on ketoconazole (the active ingredients of Ketoconazole) and Ketoconazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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