Lialda and Lupron drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lialda (mesalamine) and Lupron (leuprolide acetate). Common drug interactions include abortion spontaneous among females and tremor among males.

The phase IV clinical study analyzes what interactions people have when they take Lialda and Lupron. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Lialda?

Lialda has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 10,199 Lialda users. Check the latest studies of Lialda.

What is Lupron?

Lupron has active ingredients of leuprolide acetate. It is often used in endometriosis. eHealthMe is studying from 42,122 Lupron users. Check the latest studies of Lupron.



On Jul, 15, 2026

27 people who take Lialda and Lupron together, and have interactions are studied.

Lialda and Lupron drug interactions.

What are the common drug interactions of Lialda and Lupron, by gender? *:

female:

  1. Abortion spontaneous (naturally occurring miscarriage)
  2. Arthralgia (joint pain)
  3. Asthenia (weakness)
  4. Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)
  5. Depression
  6. Dizziness
  7. Dyspnoea (difficult or laboured respiration)
  8. Hypoglycaemia (deficiency of glucose in the bloodstream)
  9. Injection site erythema (redness at injection site)
  10. Injection site rash

male:

  1. Tremor (trembling or shaking movements in one or more parts of your body)
  2. Hallucination (an experience involving the perception of something not present)
  3. Diarrhoea
  4. Weight decreased
  5. Arthralgia (joint pain)
  6. Chest pain
  7. Decreased appetite
  8. Dizziness
  9. Dyspnoea (difficult or laboured respiration)
  10. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

What are the common drug interactions of Lialda and Lupron, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Vaginal haemorrhage (vaginal bleeding)
  2. Vulvovaginal pruritus (vulvovaginal severe itching)

30-39:

  1. Abortion spontaneous (naturally occurring miscarriage)
  2. Asthenia (weakness)
  3. Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)
  4. Dizziness
  5. Dyspnoea (difficult or laboured respiration)
  6. Hypoglycaemia (deficiency of glucose in the bloodstream)
  7. Injection site erythema (redness at injection site)
  8. Injection site rash
  9. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)

40-49:

n/a

50-59:

  1. Arthralgia (joint pain)
  2. Depression
  3. Psoriasis (immune-mediated disease that affects the skin)

60+:

  1. Tremor (trembling or shaking movements in one or more parts of your body)
  2. Hallucination (an experience involving the perception of something not present)
  3. Gait disturbance
  4. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  5. Muscular weakness (muscle weakness)
  6. Pain
  7. Weight decreased
  8. Abdominal distension
  9. Abdominal pain
  10. Adenocarcinoma pancreas (cancer of pancreas)

What are the existing conditions these people have? *

  1. Prostate Cancer: 19 people, 70.37%
  2. Prostate Cancer Metastatic: 2 people, 7.41%
  3. Parkinson's Disease: 2 people, 7.41%
  4. Metastases To Bone (cancer spreads to bone): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Lialda and Lupron?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lialda and Lupron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lialda:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lupron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lialda and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lupron and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on mesalamine and leuprolide acetate (the active ingredients of Lialda and Lupron, respectively), and Lialda and Lupron (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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