1. Home
  2. Analysis
  3. Estradiol
  4. Adcal

Estradiol and Adcal drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Estradiol (estradiol) and Adcal (calcium carbonate). Common drug interactions include headache among females.

The phase IV clinical study analyzes what interactions people have when they take Estradiol and Adcal. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Estradiol?

Estradiol has active ingredients of estradiol. It is often used in menopause. eHealthMe is studying from 18,986 Estradiol users. Check the latest studies of Estradiol.

What is Adcal?

Adcal has active ingredients of calcium carbonate. eHealthMe is studying from 4,844 Adcal users. Check the latest studies of Adcal.

On Jul, 25, 2026

13 people who take Estradiol and Adcal together, and have interactions are studied.

Estradiol and Adcal drug interactions.

What are the common drug interactions of Estradiol and Adcal, by gender? *:

female:

  1. Headache (pain in head)
  2. Anxiety
  3. Dizziness
  4. Dysgeusia (disorder of the sense of taste)
  5. Hot flush (sudden feelings of heat)
  6. Insomnia (sleeplessness)
  7. Irritability
  8. Joint laxity (looseness or instability of a joint)
  9. Migraine (headache)
  10. Mood swings (an extreme or rapid change in mood)

male:

n/a

What are the common drug interactions of Estradiol and Adcal, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Nausea (feeling of having an urge to vomit)

50-59:

  1. Insomnia (sleeplessness)
  2. Irritability
  3. Joint laxity (looseness or instability of a joint)
  4. Migraine (headache)
  5. Mood swings (an extreme or rapid change in mood)
  6. Muscle spasms (muscle contraction)
  7. Nausea (feeling of having an urge to vomit)
  8. Renal impairment (severely reduced kidney function)
  9. Dyspnoea (difficult or laboured respiration)
  10. Adverse drug reaction

60+:

  1. Headache (pain in head)
  2. Vasculitis (inflammation of a blood vessel or blood vessels)

What are the existing conditions these people have? *

  1. Ill-Defined Disorder: 5 people, 38.46%
  2. Menopausal Symptoms: 3 people, 23.08%
  3. Oedema (fluid collection in tissue): 1 person, 7.69%
  4. Inflammation: 1 person, 7.69%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%
  6. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 7.69%
  7. Bone Disorder: 1 person, 7.69%
  8. Affective Disorder (mental disorder): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Estradiol and Adcal?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Estradiol and Adcal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Estradiol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Adcal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Estradiol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Adcal and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on estradiol and calcium carbonate (the active ingredients of Estradiol and Adcal, respectively), and Estradiol and Adcal (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2026 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.