Estrone and Vitamin b12 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Estrone (estrone) and Vitamin b12 (cobalamin). Common drug interactions include weight increased among females.

The phase IV clinical study analyzes what interactions people have when they take Estrone and Vitamin b12. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Estrone?

Estrone has active ingredients of estrone. eHealthMe is studying from 225 Estrone users. Check the latest studies of Estrone.

What is Vitamin b12?

Vitamin b12 has active ingredients of cobalamin. It is often used in vitamin b12 deficiency. eHealthMe is studying from 121,681 Vitamin b12 users. Check the latest studies of Vitamin b12.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 22, 2026

26 people who take Estrone and Vitamin b12 together, and have interactions are studied.

Estrone and Vitamin b12 drug interactions.

What are the common drug interactions of Estrone and Vitamin B12, by gender? *:

female:

  1. Weight increased
  2. Depression
  3. Spinal fracture (fracture in one of vertebrae)
  4. Vomiting
  5. Flushing (the warm, red condition of human skin)
  6. Memory impairment
  7. Arthralgia (joint pain)
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  9. Chest pain
  10. Colon neoplasm (cancer from uncontrolled cell growth in the colon or rectum)

male:

n/a

What are the common drug interactions of Estrone and Vitamin B12, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Drug effect increased
  2. Dysgeusia (disorder of the sense of taste)
  3. Panic attack
  4. Respiratory failure (inadequate gas exchange by the respiratory system)
  5. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  6. Therapeutic response decreased (less preventive response)

40-49:

  1. Chest pain
  2. Pulmonary hypertension (increase in blood pressure in the lung artery)
  3. Cardiovascular disorder (heart diseases)
  4. Valvular heart disease (diseases of the heart valves)

50-59:

n/a

60+:

  1. Weight increased
  2. Diarrhoea
  3. Flushing (the warm, red condition of human skin)
  4. Memory impairment
  5. Arthralgia (joint pain)
  6. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  7. Colon neoplasm (cancer from uncontrolled cell growth in the colon or rectum)
  8. Constipation
  9. Depression
  10. Dyspepsia (indigestion)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 17 people, 65.38%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 17 people, 65.38%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 19.23%
  4. Gait Disturbance: 4 people, 15.38%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 7.69%
  6. Nausea (feeling of having an urge to vomit): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Estrone and Vitamin b12?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Estrone and Vitamin b12:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Estrone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vitamin b12:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Estrone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vitamin b12 and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on estrone and cobalamin (the active ingredients of Estrone and Vitamin b12, respectively), and Estrone and Vitamin b12 (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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