Etodolac and Compazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Etodolac (etodolac) and Compazine (prochlorperazine maleate). Common drug interactions include osteomyelitis among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Etodolac and Compazine. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Etodolac?

Etodolac has active ingredients of etodolac. It is often used in arthritis. eHealthMe is studying from 9,157 Etodolac users. Check the latest studies of Etodolac.

What is Compazine?

Compazine has active ingredients of prochlorperazine maleate. It is often used in nausea and vomiting. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

29 people who take Etodolac and Compazine together, and have interactions are studied.

Etodolac and Compazine drug interactions.

What are the common drug interactions of Etodolac and Compazine, by gender? *:

female:

Osteomyelitis (infection of bone)
Osteonecrosis of jaw (death of bone of jaw)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteosclerosis (an elevation in bone density)
Pelvic pain
Spinal osteoarthritis (joint cartilage loss in spine)
Synovitis (inflammation of the synovial membrane)
Thrombosis (formation of a blood clot inside a blood vessel)
Thyroid neoplasm (tumour of thyroid)
Trigger finger

male:

Dizziness
Platelet count decreased
Sleep disorder
Visual impairment
Anxiety
Depression
Gastric cancer (stomach cancer)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Ataxia (loss of full control of bodily movements)
Balance disorder

What are the common drug interactions of Etodolac and Compazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Ataxia (loss of full control of bodily movements)
Back pain
Blood glucose increased
Blood potassium decreased
Blood pressure increased
Bone disorder
Bone marrow disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Calcification metastatic (calcium overload in body tissue)

20-29:

n/a

30-39:

n/a

40-49:

Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
Cerebral atrophy (decrement in size of brain)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness
Intervertebral disc degeneration (spinal disc degeneration)
Intervertebral disc protrusion (spinal disc protrusion)
Neuropathy peripheral (surface nerve damage)
Sleep disorder
Visual impairment
Anxiety

50-59:

Chronic kidney disease
Depression
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Renal failure (kidney dysfunction)

60+:

Alopecia (absence of hair from areas of the body)
Anxiety
Peripheral nerve lesion
Spinal column stenosis (narrowing of spinal column)
Urinary tract infection
Weight decreased
Sleep disorder
Aortic valve stenosis (narrowing of the aortic valve)
Constipation
Cushingoid (obesity and weakening of the muscles)

What are the existing conditions these people have? *

Pain: 10 people, 34.48%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 9 people, 31.03%
Weight Decreased: 6 people, 20.69%
Pain In Jaw: 6 people, 20.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 20.69%
Muscle Spasms (muscle contraction): 6 people, 20.69%
Headache (pain in head): 5 people, 17.24%
Nausea (feeling of having an urge to vomit): 5 people, 17.24%
Depression: 4 people, 13.79%
High Blood Pressure: 4 people, 13.79%

* Approximation only. Some reports may have incomplete information.

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