Etodolac and Sumatriptan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Etodolac (etodolac) and Sumatriptan (sumatriptan succinate). Common drug interactions include paraesthesia oral among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Etodolac and Sumatriptan. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Etodolac?

Etodolac has active ingredients of etodolac. It is often used in arthritis. eHealthMe is studying from 9,157 Etodolac users. Check the latest studies of Etodolac.

What is Sumatriptan?

Sumatriptan has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 18,159 Sumatriptan users. Check the latest studies of Sumatriptan.



On Aug, 11, 2026

40 people who take Etodolac and Sumatriptan together, and have interactions are studied.

Etodolac and Sumatriptan drug interactions.

What are the common drug interactions of Etodolac and Sumatriptan, by gender? *:

female:

  1. Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
  2. Periodontal disease (disease that attacks the gum and bone and around the teeth)
  3. Primary sequestrum (piece of dead bone that has become separated during the process of necrosis from normal/sound bone)
  4. Proteinuria (presence of protein in the urine)
  5. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  6. Hypoaesthesia (reduced sense of touch or sensation)
  7. Nausea (feeling of having an urge to vomit)
  8. Abdominal pain
  9. Arthralgia (joint pain)
  10. Injury

male:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Osteopenia (a condition where bone mineral density is lower than normal)
  4. Renal failure (kidney dysfunction)
  5. Renal injury (kidney injury)
  6. Bone density decreased
  7. Emotional distress
  8. Chronic kidney disease
  9. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  10. Injury

What are the common drug interactions of Etodolac and Sumatriptan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
  2. Gallbladder disorder
  3. Organ failure
  4. Injury

30-39:

  1. Abnormal dreams
  2. Myalgia (muscle pain)

40-49:

  1. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  2. Chronic kidney disease
  3. Renal failure (kidney dysfunction)
  4. Cholecystitis chronic (long lasting infection of gallbladder)
  5. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  6. Renal impairment (severely reduced kidney function)
  7. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  8. Depression
  9. Fall
  10. Fatigue (feeling of tiredness)

50-59:

  1. Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
  2. Rash
  3. Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
  4. Sleep disorder
  5. Soft tissue disorder (disease of soft tissue)
  6. Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
  7. Swelling
  8. Synovial cyst (cyst of joint filled with synovial fluid)
  9. Synovitis (inflammation of the synovial membrane)
  10. Tendonitis (a condition that causes pain and swelling of tendons)

60+:

  1. Anxiety
  2. Arthralgia (joint pain)
  3. Fall
  4. Head injury
  5. Hyperaesthesia
  6. Insomnia (sleeplessness)
  7. Mood swings (an extreme or rapid change in mood)
  8. Neuralgia (pain in one or more nerves)
  9. Neuropathy peripheral (surface nerve damage)
  10. Overdose

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 20.00%
  2. Pain: 5 people, 12.50%
  3. Birth Control: 4 people, 10.00%
  4. High Blood Cholesterol: 3 people, 7.50%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 7.50%
  6. Breast Cancer: 3 people, 7.50%
  7. Breast Cancer Metastatic: 3 people, 7.50%
  8. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 7.50%
  9. Cardiac Disorder: 2 people, 5.00%
  10. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Etodolac and Sumatriptan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Etodolac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sumatriptan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Etodolac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sumatriptan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on etodolac and sumatriptan succinate (the active ingredients of Etodolac and Sumatriptan, respectively), and Etodolac and Sumatriptan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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