Etoposide and Daptomycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Etoposide (etoposide) and Daptomycin (daptomycin). Common drug interactions include axonal neuropathy among females and atrial fibrillation among males.

The phase IV clinical study analyzes what interactions people have when they take Etoposide and Daptomycin. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Etoposide?

Etoposide has active ingredients of etoposide. eHealthMe is studying from 77,815 Etoposide users. Check the latest studies of Etoposide.

What is Daptomycin?

Daptomycin has active ingredients of daptomycin. eHealthMe is studying from 7,879 Daptomycin users. Check the latest studies of Daptomycin.

On Jul, 21, 2026

47 people who take Etoposide and Daptomycin together, and have interactions are studied.

Etoposide and Daptomycin drug interactions.

What are the common drug interactions of Etoposide and Daptomycin, by gender? *:

female:

Axonal neuropathy (dysfunction of axon nerves)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Neoplasm progression (growth of tumour)
Diffuse large b-cell lymphoma refractory (cancer of b cells, a type of white blood cell-relapsed)
Bone marrow failure
Cardiac failure congestive
Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
Fungal skin infection
Pneumonia fungal
Anaemia (lack of blood)

male:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Neutropenia (an abnormally low number of neutrophils)
Thrombocytopenia (decrease of platelets in blood)
Febrile neutropenia (fever with reduced white blood cells)
Sepsis (a severe blood infection that can lead to organ failure and death)
Drug ineffective
Dysphagia (a condition in which swallowing is difficult or painful)
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Colitis (inflammation of colon)

What are the common drug interactions of Etoposide and Daptomycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Bone marrow failure
Cardiac failure congestive
Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
Fungal skin infection
Pneumonia fungal
Drug ineffective

10-19:

Sepsis (a severe blood infection that can lead to organ failure and death)
Aplasia (defective development or congenital absence of an organ or tissue)
Aspergillus test positive
Blood magnesium decreased
Blood potassium decreased
Blood sodium decreased
Colitis (inflammation of colon)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Febrile neutropenia (fever with reduced white blood cells)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)

20-29:

Axonal neuropathy (dysfunction of axon nerves)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Retinal haemorrhage (bleeding from retina)
Visual impairment
Bacteraemia (presence of bacteria in the blood)
Decreased appetite
Dysphagia (a condition in which swallowing is difficult or painful)
Epistaxis (bleed from the nose)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Myelosuppression (a decrease in the production of blood cells)

30-39:

Acute respiratory failure
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Dyspnoea (difficult or laboured respiration)
Hypotension (abnormally low blood pressure)
Pyrexia (fever)
Sepsis (a severe blood infection that can lead to organ failure and death)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)

40-49:

Thrombocytopenia (decrease of platelets in blood)
Anaemia (lack of blood)
Leukaemia (blood or bone marrow cancer)
Disease progression
Human herpesvirus 6 infection
Multiple myeloma (cancer of the plasma cells)
Nausea (feeling of having an urge to vomit)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Pain
Pulmonary haemorrhage (acute bleeding from the lung)

50-59:

Drug ineffective
Dysphagia (a condition in which swallowing is difficult or painful)
Obstruction gastric (obstruction in stomach)
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Stenotrophomonas infection

60+:

Neutropenia (an abnormally low number of neutrophils)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Disease progression
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Drug resistance (reduction in effectiveness of a drug)
Enterococcal infection
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Fall
Febrile neutropenia (fever with reduced white blood cells)

What are the existing conditions these people have? *

Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 10 people, 21.28%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 6 people, 12.77%
Leukopenia (less number of white blood cells in blood): 5 people, 10.64%
High Blood Pressure: 5 people, 10.64%
Anaemia (lack of blood): 5 people, 10.64%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 5 people, 10.64%
Infection: 4 people, 8.51%
Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 3 people, 6.38%
Febrile Bone Marrow Aplasia (bone marrow greatly decreases or stops production of blood cells): 3 people, 6.38%
Burkitt's Lymphoma Stage Iv (blood cancer stage iv): 3 people, 6.38%

* Approximation only. Some reports may have incomplete information.

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