Etoposide and Mesalamine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Etoposide (etoposide) and Mesalamine (mesalamine). Common drug interactions include drug ineffective among females and drug ineffective among males.
The phase IV clinical study analyzes what interactions people have when they take Etoposide and Mesalamine. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.
What is Etoposide?
Etoposide has active ingredients of etoposide. eHealthMe is studying from 77,815 Etoposide users. Check the latest studies of Etoposide.
What is Mesalamine?
Mesalamine has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 28,053 Mesalamine users. Check the latest studies of Mesalamine.
29 people who take Etoposide and Mesalamine together, and have interactions are studied.

What are the common drug interactions of Etoposide and Mesalamine, by gender? *:
female:
- Drug ineffective
- Febrile neutropenia (fever with reduced white blood cells)
- Escherichia infection (bacterial infection by escherichia coli)
- Haematoma (collection of blood outside the blood vessels)
- Hepatotoxicity (chemical-driven liver damage)
- Leukopenia (less number of white blood cells in blood)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Thrombocytopenia (decrease of platelets in blood)
- Angiocentric lymphoma (extra nodal natural killer cell cancer)
- Bone pain
male:
- Drug ineffective
- Pseudomonal sepsis (pseudomonas infections are diseases caused by a bacterium from the genus pseudomonas)
- Cardiac infection (an infection of the heart)
- Central nervous system infection (infection of brain or spinal cord)
- Cerebral haemorrhage (bleeding within the brain)
- Cholecystitis (infection of gallbladder)
- Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
- Cytomegalovirus colitis (an inflammation of the colon from virus)
- Cytomegalovirus viraemia (cytomegalo virus in blood stream)
- Death
What are the common drug interactions of Etoposide and Mesalamine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Drug ineffective
- Graft versus host disease in skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin)
- Cytomegalovirus infection
- Pancreatitis (inflammation of pancreas)
- Engraftment syndrome (inflammatory condition during neutrophil recovery after hematopoietic stem cell transplantation)
10-19:
- Escherichia sepsis (bacterial infection by escherichia coli)
- Atypical mycobacterial infection (infections caused by several types of mycobacterium similar to the germ that causes tuberculosis)
- Cytomegalovirus viraemia (cytomegalo virus in blood stream)
- Disease progression
- Drug ineffective
- Febrile neutropenia (fever with reduced white blood cells)
- Graft versus host disease in skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin)
- Hepatosplenic t-cell lymphoma (neoplasm comprising medium-sized cytotoxic t-cells that show a significant sinusoidal infiltration in the liver, spleen, and bone marrow)
- Klebsiella bacteraemia (klebsiella bacteria in blood after infection to lungs)
- Mycobacterium abscessus infection (rapid growing bacterial infection)
20-29:
- Drug ineffective
- Hepatotoxicity (chemical-driven liver damage)
- Bacteraemia (presence of bacteria in the blood)
- Mycobacterial infection
- Nausea (feeling of having an urge to vomit)
- Skin infection
- Vomiting
30-39:
- Cytomegalovirus colitis (an inflammation of the colon from virus)
- Death
- Drug ineffective
- Escherichia sepsis (bacterial infection by escherichia coli)
- Hodgkin's disease nodular sclerosis stage unspecified (cancer originating from white blood cells -unspecified)
- Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung)
- Metastases to bone (cancer spreads to bone)
- Multi-organ failure (multisystem organ failure)
- Septic shock (shock due to blood infection)
40-49:
n/a
50-59:
- Pseudomonal sepsis (pseudomonas infections are diseases caused by a bacterium from the genus pseudomonas)
- Systemic candida (whole body fungal infection)
- Pseudomonal bacteraemia (p. aeruginosa cause of bacterial infections of the blood)
- Dehydration (dryness resulting from the removal of water)
- Febrile neutropenia (fever with reduced white blood cells)
- Pericardial effusion malignant (cancerous fluid around the heart)
- Pericarditis (inflammation of the pericardium)
- Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
60+:
- Bone pain
- Cardiac infection (an infection of the heart)
- Gastrointestinal infection (infection of stomach and intestine)
- Hepatic failure (liver failure)
- Hepatic haemorrhage (bleeding inside liver)
- Hepatic infection
- Hypokalaemia (low potassium)
- Hypotension (abnormally low blood pressure)
- Immunosuppression
- Interstitial lung disease
What are the existing conditions these people have? *
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 12 people, 41.38%
- Bone Marrow Conditioning Regimen: 8 people, 27.59%
- Aplastic Anemia: 5 people, 17.24%
- Takayasu's Arteritis (an inflammation of the aorta -- the artery that carries blood from the heart to the rest of the body): 2 people, 6.90%
- Small Cell Lung Cancer Extensive Stage (small cell lung cancer that has spread (metastasized) to other regions of the body such as another lobe of the lung or the brain): 2 people, 6.90%
- Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 6.90%
- Lung Cancer - Small Cell (lung cancer): 2 people, 6.90%
- Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 2 people, 6.90%
* Approximation only. Some reports may have incomplete information.
Do you take Etoposide and Mesalamine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Etoposide (77,815 reports)
- Mesalamine (28,053 reports)
Browse all drug interactions of Etoposide and Mesalamine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Etoposide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Mesalamine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Etoposide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Mesalamine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on etoposide and mesalamine (the active ingredients of Etoposide and Mesalamine, respectively), and Etoposide and Mesalamine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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