Euthyrox and Cosentyx drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Euthyrox (levothyroxine sodium) and Cosentyx (secukinumab). Common drug interactions include diabetes mellitus among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Euthyrox and Cosentyx. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Euthyrox?

Euthyrox has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 8,740 Euthyrox users. Check the latest studies of Euthyrox.

What is Cosentyx?

Cosentyx has active ingredients of secukinumab. It is often used in psoriatic arthritis. eHealthMe is studying from 187,247 Cosentyx users. Check the latest studies of Cosentyx.

On Jul, 15, 2026

50 people who take Euthyrox and Cosentyx together, and have interactions are studied.

Euthyrox and Cosentyx drug interactions.

What are the common drug interactions of Euthyrox and Cosentyx, by gender? *:

female:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Pain
Hypertension (high blood pressure)
Dizziness
Pain in extremity
Urinary tract infection
Drug ineffective
Malaise (a feeling of general discomfort or uneasiness)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Cardiac disorder

male:

Arthralgia (joint pain)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Thrombocytopenia (decrease of platelets in blood)
Neck pain
Pain
Thyroid cancer
Lung adenocarcinoma (a form of non-small cell lung cancer)
Necrosis (the death of body tissue)
Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue)
Skin infection

What are the common drug interactions of Euthyrox and Cosentyx, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Angioedema (rapid swelling of the dermis)
Drug ineffective
Eye swelling
Lip swelling
Pain in extremity
Peripheral swelling
Rash macular (small, flat red spots)
Swelling face
Urticaria (rash of round, red welts on the skin that itch intensely)
Dizziness

40-49:

Arthralgia (joint pain)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Neck pain
Pain
Thyroid cancer
Abdominal pain
Diarrhoea
Pyrexia (fever)
Encephalitis (inflammation of the brain)
Exercise tolerance decreased

50-59:

Influenza
Myalgia (muscle pain)
Pyrexia (fever)
Erythema (redness of the skin)
Maternal exposure during pregnancy (use of substance during pregnancy)
Mood altered (changes in mood)
Pruritus (severe itching of the skin)
Scratch
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)

60+:

Abdominal pain
Arthralgia (joint pain)
Decreased appetite
Diffuse large b-cell lymphoma stage iv (cancer of b cells, a type of white blood cell-stage iv)
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Dysstasia (difficulty in standing)
Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Gait disturbance

What are the existing conditions these people have? *

Ankylosing Spondylitis (type of arthritis affecting the spine): 20 people, 40.00%
Psoriasis (immune-mediated disease that affects the skin): 18 people, 36.00%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 12 people, 24.00%
High Blood Pressure: 9 people, 18.00%
Thyroid Diseases: 8 people, 16.00%
High Blood Cholesterol: 4 people, 8.00%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

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