Evamist and Metformin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Evamist (estradiol) and Metformin (metformin hydrochloride). Common drug interactions include post laminectomy syndrome among females and respiratory disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Evamist and Metformin. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Evamist?

Evamist has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 671 Evamist users. Check the latest studies of Evamist.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,354 Metformin users. Check the latest studies of Metformin.

On Jul, 14, 2026

38 people who take Evamist and Metformin together, and have interactions are studied.

Evamist and Metformin drug interactions.

What are the common drug interactions of Evamist and Metformin, by gender? *:

female:

Post laminectomy syndrome
Bacterial infection
Kidney infection
Salmonellosis (an infection with salmonella bacteria)
Fall
Haemorrhoidal haemorrhage (bleeding from the haemorrhoids)
Injection site pain
Malaise (a feeling of general discomfort or uneasiness)
Anaemia (lack of blood)
Cellulitis (infection under the skin)

male:

Respiratory disorder (respiratory disease)
Scar

What are the common drug interactions of Evamist and Metformin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Chronic kidney disease
Vomiting
Blood potassium decreased
Fatigue (feeling of tiredness)
Gastrointestinal disorder (functional problems of gastrointestinal tract)

50-59:

Cholecystitis (infection of gallbladder)
Complication of device insertion
Feeling hot

60+:

Drug ineffective
Application site dryness
Anal haemorrhage
Arthropathy
Asthenia (weakness)
Bacterial infection
Blood iron decreased
Cellulitis (infection under the skin)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Drug hypersensitivity

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 13 people, 34.21%
Transient Hypogammaglobulinaemia Of Infancy (delayed onset of immunoglobulin production in infants): 13 people, 34.21%
Immunodeficiency Common Variable: 12 people, 31.58%
Humoral Immune Defect (impairment of humoral immunity): 10 people, 26.32%
High Blood Pressure: 9 people, 23.68%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 15.79%
High Blood Cholesterol: 5 people, 13.16%
Pain: 5 people, 13.16%
Infection: 4 people, 10.53%
Hypersensitivity: 4 people, 10.53%

* Approximation only. Some reports may have incomplete information.

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