Evening primrose and Lexapro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Evening primrose (evening primrose oil) and Lexapro (escitalopram oxalate). Common drug interactions include malaise among females.

The phase IV clinical study analyzes what interactions people have when they take Evening primrose and Lexapro. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Evening primrose?

Evening primrose has active ingredients of evening primrose oil. It is often used in breast pain. eHealthMe is studying from 1,794 Evening primrose users. Check the latest studies of Evening primrose.

What is Lexapro?

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.

On Jul, 12, 2026

40 people who take Evening primrose and Lexapro together, and have interactions are studied.

Evening primrose and Lexapro drug interactions.

What are the common drug interactions of Evening Primrose and Lexapro, by gender? *:

female:

Malaise (a feeling of general discomfort or uneasiness)
Somnolence (a state of near-sleep, a strong desire for sleep)
Gait disturbance
Pain
Suicidal ideation
Back disorder
Hysterectomy
Malignant melanoma (skin cancer rises from melancytes)
Abortion spontaneous (naturally occurring miscarriage)
Alopecia (absence of hair from areas of the body)

male:

n/a

What are the common drug interactions of Evening Primrose and Lexapro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abortion spontaneous (naturally occurring miscarriage)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Emotional disorder
Injury
Maternal exposure during pregnancy (use of substance during pregnancy)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Pain
Pregnancy with implant contraceptive
Psychological trauma

30-39:

Visual acuity reduced (reduced clearness of vision)
Visual field defect
Visual impairment
Wheezing (a high-pitched whistling sound made while you breath)
Back disorder
Drug hypersensitivity
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hysterectomy
Malignant melanoma (skin cancer rises from melancytes)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

40-49:

Abdominal discomfort
Flushing (the warm, red condition of human skin)

50-59:

Malaise (a feeling of general discomfort or uneasiness)
Decreased appetite
Drug dependence
Gait disturbance
Hypoaesthesia (reduced sense of touch or sensation)
Somnolence (a state of near-sleep, a strong desire for sleep)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Cough
Deafness
Globulins decreased

60+:

Alopecia (absence of hair from areas of the body)
Blood magnesium decreased
Pulmonary thrombosis (scarring in the lungs)
Rash pruritic (redness with itching)
Thrombocytopenia (decrease of platelets in blood)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Tumour marker increased
Urinary tract infection
Vitamin b12 decreased
Vitamin d deficiency

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 15 people, 37.50%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 11 people, 27.50%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 9 people, 22.50%
Multiple Myeloma (cancer of the plasma cells): 4 people, 10.00%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 10.00%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 10.00%
Pain: 3 people, 7.50%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 5.00%
Hypersensitivity: 2 people, 5.00%
High Blood Cholesterol: 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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