Evista and Norflex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Evista (raloxifene hydrochloride) and Norflex (orphenadrine citrate). Common drug interactions include dysphagia among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Evista and Norflex. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Evista?

Evista has active ingredients of raloxifene hydrochloride. It is often used in osteoporosis. eHealthMe is studying from 25,891 Evista users. Check the latest studies of Evista.

What is Norflex?

Norflex has active ingredients of orphenadrine citrate. It is often used in muscle spasms. eHealthMe is studying from 1,951 Norflex users. Check the latest studies of Norflex.

On Jul, 06, 2026

15 people who take Evista and Norflex together, and have interactions are studied.

What are the common drug interactions of Evista and Norflex, by gender? *:

female:

Dysphagia (a condition in which swallowing is difficult or painful)
Excessive eye blinking (excessive blinking is dry eyes)
Fatigue (feeling of tiredness)
Joint swelling
Nasal dryness (dry nose)
Spinal compression fracture (fracture due to spinal compression on bone)
Abdominal distension
Abdominal pain
Activities of daily living impaired
Adverse reaction

male:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)

What are the common drug interactions of Evista and Norflex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Breast cancer female
Hip fracture
Drug ineffective
Excessive eye blinking (excessive blinking is dry eyes)
Fatigue (feeling of tiredness)
Gait disturbance
Glaucoma (increased fluid pressure in the eye with vision loss)
Joint swelling
Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)

What are the existing conditions these people have? *

High Blood Pressure: 3 people, 20.00%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 2 people, 13.33%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 2 people, 13.33%
Weakness: 1 person, 6.67%
Musculoskeletal Disorder (disease of the body's muscles, joints, tendons, ligaments and nerves): 1 person, 6.67%
Movement - Uncoordinated: 1 person, 6.67%
Knee Deformity (functional disability of knee): 1 person, 6.67%
Infection: 1 person, 6.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.67%
Gastric Ulcer (stomach ulcer): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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