Evoxac and Prednisolone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Evoxac (cevimeline hydrochloride) and Prednisolone (prednisolone). Common drug interactions include delirium among females and herpes zoster among males.

The phase IV clinical study analyzes what interactions people have when they take Evoxac and Prednisolone. It is created by eHealthMe based on reports of 84 people who take the same drugs from the FDA, and is updated regularly.

What is Evoxac?

Evoxac has active ingredients of cevimeline hydrochloride. It is often used in sjogren syndrome. eHealthMe is studying from 2,028 Evoxac users. Check the latest studies of Evoxac.

What is Prednisolone?

Prednisolone has active ingredients of prednisolone. It is often used in rheumatoid arthritis. eHealthMe is studying from 212,675 Prednisolone users. Check the latest studies of Prednisolone.

On Aug, 10, 2026

84 people who take Evoxac and Prednisolone together, and have interactions are studied.

Evoxac and Prednisolone drug interactions.

What are the common drug interactions of Evoxac and Prednisolone, by gender? *:

female:

Delirium (wild excitement)
Dry eye (lack of adequate tears)
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Gastroenteritis (inflammation of stomach and intestine)
Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
Iron deficiency anaemia
Nasopharyngitis (inflammation of the nasopharynx)
Blood creatine phosphokinase increased
Hyperlipidaemia (presence of excess lipids in the blood)
Lupus nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue)

male:

Herpes zoster
Interstitial lung disease
Faeces discoloured
Liver disorder (liver diseases)
Lymphoma (cancer that begins in immune system cells)
Haemoglobin decreased
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Organising pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue)
White blood cell count decreased
Anaemia (lack of blood)

What are the common drug interactions of Evoxac and Prednisolone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Iron deficiency anaemia
Nasopharyngitis (inflammation of the nasopharynx)
Blood creatine phosphokinase increased
Gastroenteritis (inflammation of stomach and intestine)
Hyperlipidaemia (presence of excess lipids in the blood)
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Osteonecrosis (death of bone)
Otitis externa (external ear infection)
Purpura (purplish discoloration of the skin)

30-39:

Diarrhoea
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Menstruation irregular
Oedema (fluid collection in tissue)
Seasonal allergy (allergic condition due to certain season)
Upper respiratory tract infection
Upper respiratory tract inflammation
Autoimmune thrombocytopenia (isolated low platelet count (thrombocytopenia) with normal bone marrow and the absence of other causes of thrombocytopenia)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)

40-49:

Cerebral infarction (less blood supply to brain resulting tissue damage)
Decreased appetite
Delirium (wild excitement)
Gamma-glutamyltransferase increased
Nephrogenic anaemia (anaemia due to kidney disease)
Platelet count decreased
Pyrexia (fever)
Renal failure chronic (long lasting kidney dysfunction)
Restlessness (not able to rest)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)

50-59:

Extranodal marginal zone b-cell lymphoma (malt type) (cancer originating from b cells in the marginal zone of the malt)
Flushing (the warm, red condition of human skin)
Nausea (feeling of having an urge to vomit)
Neutropenia (an abnormally low number of neutrophils)
Palpitations (feelings or sensations that your heart is pounding or racing)
Pneumonia
Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
Pyrexia (fever)
Rash
White blood cell count decreased

60+:

Headache (pain in head)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Pulmonary congestion (congestion in the lungs)
White blood cell count decreased
Aortic aneurysm rupture (enlarged aortic artery rapture caused by a weakening of the artery wall)
Gastric ulcer (stomach ulcer)
Blood pressure increased
Eyelid oedema (eyelids are swollen and contain excessive fluid)
Fluid retention (an abnormal accumulation of fluid in the blood)
Flushing (the warm, red condition of human skin)

What are the existing conditions these people have? *

Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 15 people, 17.86%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 9 people, 10.71%
Iron Deficiency Anaemia: 8 people, 9.52%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 8 people, 9.52%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 7 people, 8.33%
Hyperlipidaemia (presence of excess lipids in the blood): 7 people, 8.33%
High Blood Pressure: 7 people, 8.33%
Diarrhea: 6 people, 7.14%
Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 5 people, 5.95%
Joint Pain: 5 people, 5.95%

* Approximation only. Some reports may have incomplete information.

Do you take Evoxac and Prednisolone?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously