Evzio and Gabapentin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Evzio (naloxone hydrochloride) and Gabapentin (gabapentin). Common drug interactions include constipation among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Evzio and Gabapentin. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Evzio?

Evzio has active ingredients of naloxone hydrochloride. eHealthMe is studying from 120 Evzio users. Check the latest studies of Evzio.

What is Gabapentin?

Gabapentin has active ingredients of gabapentin. It is often used in peripheral neuropathy. eHealthMe is studying from 322,987 Gabapentin users. Check the latest studies of Gabapentin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

20 people who take Evzio and Gabapentin together, and have interactions are studied.

What are the common drug interactions of Evzio and Gabapentin, by gender? *:

female:

Constipation
Fibromyalgia (a long-term condition which causes pain all over the body)
Hyperventilation
Scar
Weight increased
Arthropathy
Exostosis (formation of new bone on the surface of a bone)
Headache (pain in head)
Intervertebral disc protrusion (spinal disc protrusion)
Surgery

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Dizziness
Drug ineffective
Foot fracture
Hospitalisation
Intervertebral disc disorder (spinal disc disorder)
Nausea (feeling of having an urge to vomit)
Chronic kidney disease
Emotional distress

What are the common drug interactions of Evzio and Gabapentin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Drug ineffective

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Constipation
Emotional distress
Exostosis (formation of new bone on the surface of a bone)
Fibromyalgia (a long-term condition which causes pain all over the body)
Hyperventilation
Intervertebral disc protrusion (spinal disc protrusion)
Osteoporosis (bones weak and more likely to break)

60+:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Dysphonia (speech disorder attributable to a disorder of phonation)
Vocal cord disorder
Chronic kidney disease
Diarrhoea
Dizziness
Intervertebral disc disorder (spinal disc disorder)
Nausea (feeling of having an urge to vomit)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 40.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 20.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 15.00%
Hiv Infection: 3 people, 15.00%
Pain: 2 people, 10.00%
Overdose: 2 people, 10.00%
Neoplasm Malignant (cancer tumour): 2 people, 10.00%
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body): 1 person, 5.00%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 5.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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