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Exalgo and Levaquin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Exalgo (hydromorphone hydrochloride) and Levaquin (levofloxacin). Common drug interactions include hyperhidrosis among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Exalgo and Levaquin. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Exalgo?

Exalgo has active ingredients of hydromorphone hydrochloride. It is often used in chronic pain. eHealthMe is studying from 9,847 Exalgo users. Check the latest studies of Exalgo.

What is Levaquin?

Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. eHealthMe is studying from 56,638 Levaquin users. Check the latest studies of Levaquin.

On Jul, 26, 2026

12 people who take Exalgo and Levaquin together, and have interactions are studied.

Exalgo and Levaquin drug interactions.

What are the common drug interactions of Exalgo and Levaquin, by gender? *:

female:

  1. Hyperhidrosis (abnormally increased sweating)
  2. Neoplasm malignant (cancer tumour)
  3. Osteonecrosis of jaw (death of bone of jaw)
  4. Pyrexia (fever)
  5. Bone loss
  6. Diarrhoea
  7. Flushing (the warm, red condition of human skin)

male:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Nephropathy (damage to or disease of a kidney)
  4. Renal injury (kidney injury)
  5. Nephrogenic anaemia (anaemia due to kidney disease)
  6. Hyperchlorhydria (gastric acid levels are higher in stomach)
  7. Rebound effect (take-back effect)

What are the common drug interactions of Exalgo and Levaquin, by age (0-1 to 60+)? *:

0-1:

  1. Drug exposure during pregnancy
  2. Drug withdrawal syndrome neonatal (prenatal nas is caused by discontinuation of drugs taken by the pregnant mother)
  3. Ligament rupture (tear in ligament)
  4. Premature baby
  5. Tendon rupture (tear of tendon)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Cough: 10 people, 83.33%
  2. Muscle Spasms (muscle contraction): 9 people, 75.00%
  3. Diabetes: 9 people, 75.00%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 75.00%
  5. Headache (pain in head): 9 people, 75.00%
  6. High Blood Cholesterol: 9 people, 75.00%
  7. High Blood Pressure: 9 people, 75.00%
  8. Constipation: 9 people, 75.00%
  9. Chest Pain: 9 people, 75.00%
  10. Indigestion: 9 people, 75.00%

* Approximation only. Some reports may have incomplete information.

Do you take Exalgo and Levaquin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Exalgo and Levaquin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Exalgo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Levaquin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Exalgo and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Levaquin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on hydromorphone hydrochloride and levofloxacin (the active ingredients of Exalgo and Levaquin, respectively), and Exalgo and Levaquin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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