Excedrin and Qnasl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Excedrin (acetaminophen; aspirin; caffeine) and Qnasl (beclomethasone dipropionate). Common drug interactions include anaesthetic complication among females and erythema among males.

The phase IV clinical study analyzes what interactions people have when they take Excedrin and Qnasl. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Excedrin?

Excedrin has active ingredients of acetaminophen; aspirin; caffeine. It is often used in headache. eHealthMe is studying from 22,740 Excedrin users. Check the latest studies of Excedrin.

What is Qnasl?

Qnasl has active ingredients of beclomethasone dipropionate. It is often used in allergies. eHealthMe is studying from 1,984 Qnasl users. Check the latest studies of Qnasl.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 25, 2026

12 people who take Excedrin and Qnasl together, and have interactions are studied.

Excedrin and Qnasl drug interactions.

What are the common drug interactions of Excedrin and Qnasl, by gender? *:

female:

  1. Anaesthetic complication
  2. Application site inflammation
  3. Application site pain
  4. Application site reaction
  5. Application site vesicles (small bubble within a cell at application site)
  6. Application site warmth
  7. Burns second degree
  8. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  9. Ear infection
  10. Fatigue (feeling of tiredness)

male:

  1. Erythema (redness of the skin)
  2. Swelling
  3. Urticaria (rash of round, red welts on the skin that itch intensely)

What are the common drug interactions of Excedrin and Qnasl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Application site vesicles (small bubble within a cell at application site)
  2. Application site warmth
  3. Burns second degree
  4. Abasia (inability to walk)
  5. Application site erythema (redness of the skin at application site)
  6. Application site inflammation
  7. Application site pain
  8. Application site reaction

40-49:

  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
  3. Weight decreased
  4. Activities of daily living impaired
  5. Fatigue (feeling of tiredness)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 75.00%
  2. Migraine (headache): 1 person, 8.33%
  3. Immunodeficiency Common Variable: 1 person, 8.33%
  4. Fungal Nail Infection: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Excedrin and Qnasl?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Excedrin and Qnasl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Excedrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Qnasl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Excedrin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Qnasl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; aspirin; caffeine and beclomethasone dipropionate (the active ingredients of Excedrin and Qnasl, respectively), and Excedrin and Qnasl (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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