Excedrin and Xalatan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Excedrin (acetaminophen; aspirin; caffeine) and Xalatan (latanoprost). Common drug interactions include myocardial infarction among females and bladder transitional cell carcinoma among males.

The phase IV clinical study analyzes what interactions people have when they take Excedrin and Xalatan. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Excedrin?

Excedrin has active ingredients of acetaminophen; aspirin; caffeine. It is often used in headache. eHealthMe is studying from 22,740 Excedrin users. Check the latest studies of Excedrin.

What is Xalatan?

Xalatan has active ingredients of latanoprost. It is often used in glaucoma. eHealthMe is studying from 25,550 Xalatan users. Check the latest studies of Xalatan.

On Jul, 11, 2026

19 people who take Excedrin and Xalatan together, and have interactions are studied.

What are the common drug interactions of Excedrin and Xalatan, by gender? *:

female:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Nausea (feeling of having an urge to vomit)
Neck pain
Transverse sinus thrombosis (a blood clot in transverse sinus)
Urinary tract infection
Vomiting
Abdominal pain
Abscess (pus)
Asthenia (weakness)

male:

Bladder transitional cell carcinoma (types of bladder cancer)

What are the common drug interactions of Excedrin and Xalatan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)

30-39:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Drug ineffective
Respiratory tract infection
Urinary tract infection

40-49:

Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Neck pain
Transverse sinus thrombosis (a blood clot in transverse sinus)
Injury

50-59:

Injury
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Abdominal pain
Abscess (pus)
Constipation
Feeling hot
Flushing (the warm, red condition of human skin)
Malaise (a feeling of general discomfort or uneasiness)
Pruritus (severe itching of the skin)
Skin cancer

60+:

Constipation
Drug ineffective
Dysphonia (speech disorder attributable to a disorder of phonation)
Faeces hard
Pericardial effusion (fluid around the heart)
Weight decreased

What are the existing conditions these people have? *

Migraine (headache): 5 people, 26.32%
Stress And Anxiety: 4 people, 21.05%
Pain: 4 people, 21.05%
Anaemia (lack of blood): 4 people, 21.05%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 21.05%
Heavy Or Prolong Menstrual Bleeding: 4 people, 21.05%
Multiple Myeloma (cancer of the plasma cells): 3 people, 15.79%
Birth Control: 3 people, 15.79%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 15.79%
High Blood Cholesterol: 3 people, 15.79%

* Approximation only. Some reports may have incomplete information.

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