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Afinitor and Nail abnormalities - a phase IV clinical study of FDA data

Summary:

Nail abnormalities is reported as a side effect among people who take Afinitor (everolimus), especially for people who are female, 50-59 old, have been taking the drug for 6 - 12 months also take Sertraline, and have Drowsiness.

The phase IV clinical study analyzes which people have Nail abnormalities when taking Afinitor. It is created by eHealthMe based on reports of 41,609 people who have side effects when taking Afinitor from the FDA, and is updated regularly.

What is Afinitor?

Afinitor has active ingredients of everolimus. It is often used in breast cancer metastatic. eHealthMe is studying from 41,680 Afinitor users. Check the latest studies of Afinitor.

What is Nail abnormalities?

Nail abnormalities (abnormal nail) is found to be associated with 211 drugs and 652 conditions by eHealthMe. Check the latest studies of Nail abnormalities.

On Jul, 11, 2026

41,609 people reported to have side effects when taking Afinitor.
Among them, 15 people (0.04%) have Nail abnormalities.

Could Afinitor cause Nail abnormalities?

Among these 15 people:

How long have people been on Afinitor when they have Nail abnormalities? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Nail abnormalities when taking Afinitor? *

  • female: 80 %
  • male: 20 %

What is the age of people who have Nail abnormalities when taking Afinitor? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 22.22 %
  • 50-59: 55.56 %
  • 60+: 22.22 %

What are other drugs people take besides Afinitor? *

  1. Sertraline: 9 people, 60.00%
  2. Tramadol: 5 people, 33.33%
  3. Ranitidine: 5 people, 33.33%
  4. Quetiapine Fumarate: 5 people, 33.33%
  5. Metoclopramide: 5 people, 33.33%
  6. Folic Acid: 5 people, 33.33%
  7. Desloratadine: 5 people, 33.33%
  8. Carvedilol: 5 people, 33.33%
  9. Calcitriol: 5 people, 33.33%
  10. Bisacodyl: 5 people, 33.33%

What are other side effects people have besides Nail abnormalities? *

  1. Dry Skin: 11 people, 73.33%
  2. Rashes (redness): 11 people, 73.33%
  3. Skin Exfoliation (removal of the oldest dead skin cells): 11 people, 73.33%
  4. Weight Decreased: 10 people, 66.67%
  5. Stomatitis (inflammation of mucous membrane of mouth): 10 people, 66.67%
  6. Nausea (feeling of having an urge to vomit): 10 people, 66.67%
  7. Cataract (clouding of the lens inside the eye): 10 people, 66.67%
  8. Pain: 10 people, 66.67%
  9. Tumor: 10 people, 66.67%
  10. Arrhythmias (irregular heartbeat): 9 people, 60.00%

What are the existing conditions these people have? *

  1. Uterine Fibroids (benign growths of the muscle inside the uterus): 9 people, 60.00%
  2. Drowsiness: 9 people, 60.00%
  3. Renal Cell Carcinoma (a kidney cancer): 2 people, 13.33%
  4. Neoplasm Malignant (cancer tumour): 1 person, 6.67%
  5. Fungal Nail Infection: 1 person, 6.67%
  6. Breast Cancer Female: 1 person, 6.67%
  7. Angiomyolipoma (most common benign tumour of the kidney): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Afinitor and have Nail abnormalities?

- Check whether Nail abnormalities is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Afinitor:

Nail abnormalities treatments and more:

How severe was Nail abnormalities and when was it recovered:

Expand to all the drugs that have ingredients of everolimus:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Afinitor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nail abnormalities:

Browse all the conditions that are associated with Nail abnormalities:

How the study uses the data?

The study uses data from the FDA. It is based on everolimus (the active ingredients of Afinitor) and Afinitor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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