Exforge hct and Lasix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Exforge hct (amlodipine; hydrochlorothiazide; valsartan) and Lasix (furosemide). Common drug interactions include somnolence among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Exforge hct and Lasix. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Exforge hct?

Exforge hct has active ingredients of amlodipine; hydrochlorothiazide; valsartan. It is often used in high blood pressure. eHealthMe is studying from 4,095 Exforge hct users. Check the latest studies of Exforge hct.

What is Lasix?

Lasix has active ingredients of furosemide. It is often used in swelling. eHealthMe is studying from 210,439 Lasix users. Check the latest studies of Lasix.



On Jul, 12, 2026

48 people who take Exforge hct and Lasix together, and have interactions are studied.

Exforge hct and Lasix drug interactions.

What are the common drug interactions of Exforge Hct and Lasix, by gender? *:

female:

  1. Somnolence (a state of near-sleep, a strong desire for sleep)
  2. Thalamic infarction (tissue death of thalamus part of brain)
  3. General physical health deterioration (weak health status)
  4. Oedema peripheral (superficial swelling)
  5. Acute respiratory failure
  6. Alanine aminotransferase increased
  7. Anaphylactic reaction (serious allergic reaction)
  8. Arterial disorder
  9. Arteriosclerosis (thickening and hardening of arteries)
  10. Asthenia (weakness)

male:

  1. Headache (pain in head)
  2. Tooth disorder (tooth disease)
  3. Hypoxic-ischaemic encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total)
  4. Loss of consciousness
  5. Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
  6. Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
  7. Toothache (tooth pain)
  8. Torsade de pointes (a abnormal heart rate with abnormal beating pattern)
  9. Ventricular fibrillation (abnormally irregular heart rhythm)
  10. Vomiting

What are the common drug interactions of Exforge Hct and Lasix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Hyperkalaemia (damage to or disease of the kidney)
  2. Toothache (tooth pain)
  3. Hypercalcaemia (elevated calcium (ca+) level in the blood)
  4. Tooth disorder (tooth disease)
  5. Headache (pain in head)
  6. Pneumonia

30-39:

n/a

40-49:

n/a

50-59:

  1. Cataract (clouding of the lens inside the eye)
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  3. Gastric infection (infection of stomach)
  4. Heart rate decreased
  5. Joint swelling
  6. Loss of consciousness
  7. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  8. Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
  9. Vomiting
  10. Cerebral haemorrhage (bleeding within the brain)

60+:

  1. Thrombocytopenia (decrease of platelets in blood)
  2. Hypokalaemia (low potassium)
  3. Oedema (fluid collection in tissue)
  4. Syncope (loss of consciousness with an inability to maintain postural tone)
  5. Unresponsive to stimuli
  6. Depression
  7. Hypotension (abnormally low blood pressure)
  8. Oedema peripheral (superficial swelling)
  9. Renal failure (kidney dysfunction)
  10. Asthenia (weakness)

What are the existing conditions these people have? *

  1. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 15 people, 31.25%
  2. Diabetes: 8 people, 16.67%
  3. High Blood Cholesterol: 6 people, 12.50%
  4. Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 4 people, 8.33%
  5. Oedema (fluid collection in tissue): 4 people, 8.33%
  6. Constipation: 4 people, 8.33%
  7. Insomnia (sleeplessness): 4 people, 8.33%
  8. Back Pain: 3 people, 6.25%
  9. Carotid Artery Stenosis (narrowing of carotid artery): 3 people, 6.25%
  10. Type 2 Diabetes: 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Exforge hct and Lasix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Exforge hct:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lasix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Exforge hct and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lasix and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on amlodipine; hydrochlorothiazide; valsartan and furosemide (the active ingredients of Exforge hct and Lasix, respectively), and Exforge hct and Lasix (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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