Exforge hct and Seroquel drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Exforge hct (amlodipine; hydrochlorothiazide; valsartan) and Seroquel (quetiapine fumarate). Common drug interactions include drug ineffective among females and arthritis among males.
The phase IV clinical study analyzes what interactions people have when they take Exforge hct and Seroquel. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.
What is Exforge hct?
Exforge hct has active ingredients of amlodipine; hydrochlorothiazide; valsartan. It is often used in high blood pressure. eHealthMe is studying from 4,095 Exforge hct users. Check the latest studies of Exforge hct.
What is Seroquel?
Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.
14 people who take Exforge hct and Seroquel together, and have interactions are studied.

What are the common drug interactions of Exforge Hct and Seroquel, by gender? *:
female:
- Drug ineffective
- Fall
- Anxiety
- Hypotension (abnormally low blood pressure)
- Arrhythmia (irregular heartbeat)
- Blood pressure fluctuation
- Dysuria (painful or difficult urination)
- Extrasystoles
- Fatigue (feeling of tiredness)
- Fluid retention (an abnormal accumulation of fluid in the blood)
male:
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Bone loss
- Osteoporosis (bones weak and more likely to break)
- Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
- Tibia fracture (fracture of lower leg bone)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Asthenia (weakness)
- Depressed mood
- Irritability
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
What are the common drug interactions of Exforge Hct and Seroquel, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Blood glucose increased
- Urinary tract infection
- Viith nerve paralysis
- Feeling drunk
- Hypersomnia (excessive daytime sleepiness (eds))
- Somnolence (a state of near-sleep, a strong desire for sleep)
30-39:
n/a
40-49:
n/a
50-59:
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Bone loss
- Bone pain
- Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Lower limb fracture
- Multiple fractures
- Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
- Onychomycosis (fungal infection of the nail)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
60+:
- Fall
- Arrhythmia (irregular heartbeat)
- Peripheral swelling
- Renal disorder (kidney disease)
- Spinal disorder (disease of spine a back bone)
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Urinary retention (the inability to completely or partially empty the bladder)
- Anxiety
- Fear
- Feeling of despair
What are the existing conditions these people have? *
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 28.57%
- Essential Hypertension (primary hypertension): 3 people, 21.43%
- Diabetes: 2 people, 14.29%
- Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 2 people, 14.29%
- Arrhythmias (irregular heartbeat): 2 people, 14.29%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 7.14%
- Nervous System Disorder (a general class of medical conditions affecting the nervous system): 1 person, 7.14%
- Multiple Allergies (allergy to multiple agents): 1 person, 7.14%
- Laxative Supportive Care: 1 person, 7.14%
- Indigestion: 1 person, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Exforge hct and Seroquel?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Exforge hct (4,095 reports)
- Seroquel (120,285 reports)
Browse all drug interactions of Exforge hct and Seroquel:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Exforge hct:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Seroquel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Exforge hct and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Seroquel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Mati?, K., & Pele?, A. M. , "Drug-induced toxic hepatitis associated with the combination of quetiapine and fluphenazine: A case report", The European Journal of Psychiatry, 2018 Jan .
- Shah Z, Londhe V, "Influence of various media on the dissolution profiles of immediate-release quetiapine tablets in India", Dissolution Technologies, 2016 Feb .
- Mati?, K., & Pele?, A. M. , "Drug-induced toxic hepatitis associated with the combination of quetiapine and fluphenazine: A case report", The European Journal of Psychiatry, 2018 Jan .
- Shah Z, Londhe V, "Influence of various media on the dissolution profiles of immediate-release quetiapine tablets in India", Dissolution Technologies, 2016 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on amlodipine; hydrochlorothiazide; valsartan and quetiapine fumarate (the active ingredients of Exforge hct and Seroquel, respectively), and Exforge hct and Seroquel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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