Exforge and Dupixent drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Exforge (amlodipine besylate; valsartan) and Dupixent (dupilumab). Common drug interactions include injection site pruritus among females and muscle rupture among males.

The phase IV clinical study analyzes what interactions people have when they take Exforge and Dupixent. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Exforge?

Exforge has active ingredients of amlodipine besylate; valsartan. It is often used in high blood pressure. eHealthMe is studying from 13,350 Exforge users. Check the latest studies of Exforge.

What is Dupixent?

Dupixent has active ingredients of dupilumab. eHealthMe is studying from 257,630 Dupixent users. Check the latest studies of Dupixent.

On Jul, 04, 2026

21 people who take Exforge and Dupixent together, and have interactions are studied.

What are the common drug interactions of Exforge and Dupixent, by gender? *:

female:

Injection site pruritus (severe itching at injection site)
Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
Pruritus (severe itching of the skin)
Asthma
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)

male:

Muscle rupture (tear in muscle)
Cataract (clouding of the lens inside the eye)
Back pain
Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Discomfort
Drug ineffective
Dry eye (lack of adequate tears)
Ear infection
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Immune system disorder

What are the common drug interactions of Exforge and Dupixent, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Hyperhidrosis (abnormally increased sweating)
Pyrexia (fever)
Sinusitis (inflammation of sinus)
Drug ineffective
Ear infection
Immune system disorder
Skin reaction

60+:

Injection site pruritus (severe itching at injection site)
Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
Tracheomalacia (a structural abnormality of the tracheal (windpipe) cartilage resulting in the collapse of the wall of the trachea which obstructs the airway)
Vitiligo (pigment is lost from areas of the skin)
Pruritus (severe itching of the skin)
Cataract (clouding of the lens inside the eye)
Muscle rupture (tear in muscle)
Post procedural complication
Psoriasis (immune-mediated disease that affects the skin)
Upper respiratory tract infection

What are the existing conditions these people have? *

Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 9 people, 42.86%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 14.29%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 14.29%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 14.29%
Asthma: 3 people, 14.29%
Urticaria (rash of round, red welts on the skin that itch intensely): 2 people, 9.52%
Neurodermatitis (a skin disorder characterized by long lasting itching and scratching): 2 people, 9.52%
Idiopathic Urticaria (allergic reactions, presence of hives with unknown cause): 2 people, 9.52%
High Blood Pressure: 2 people, 9.52%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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