Exforge and Novolog drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Exforge (amlodipine besylate; valsartan) and Novolog (insulin aspart recombinant). Common drug interactions include drug ineffective among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Exforge and Novolog. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.

What is Exforge?

Exforge has active ingredients of amlodipine besylate; valsartan. It is often used in high blood pressure. eHealthMe is studying from 13,350 Exforge users. Check the latest studies of Exforge.

What is Novolog?

Novolog has active ingredients of insulin aspart recombinant. It is often used in diabetes. eHealthMe is studying from 56,160 Novolog users. Check the latest studies of Novolog.



On Jul, 20, 2026

77 people who take Exforge and Novolog together, and have interactions are studied.

Exforge and Novolog drug interactions.

What are the common drug interactions of Exforge and Novolog, by gender? *:

female:

  1. Drug ineffective
  2. Dyspnoea (difficult or laboured respiration)
  3. Dyspnoea exertional (breathlessness or shortness of breath)
  4. Glycosylated haemoglobin increased
  5. Hypercoagulation (increased tendency for clotting of the blood)
  6. Hypernatraemia (an abnormally high plasma concentration of sodium ions)
  7. Hypervolaemia (abnormally increased volume of blood)
  8. Influenza
  9. Memory impairment
  10. Muscle spasms (muscle contraction)

male:

  1. Chronic kidney disease
  2. Anaemia (lack of blood)
  3. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  4. Acne (skin problems that cause pimples)
  5. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  7. Blood glucose increased
  8. Chest pain
  9. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  10. Diplopia (double vision)

What are the common drug interactions of Exforge and Novolog, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Chronic kidney disease
  2. Drug ineffective
  3. Urine ketone body present
  4. Abdominal pain
  5. Abscess (pus)
  6. Agitation (state of anxiety or nervous excitement)
  7. Alanine aminotransferase increased
  8. Antinuclear antibody positive
  9. Aspartate aminotransferase increased
  10. Asthma

50-59:

  1. Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)
  2. Abasia (inability to walk)
  3. Alopecia (absence of hair from areas of the body)
  4. Aphasia (damage to the parts of the brain that control language)
  5. Asthenia (weakness)
  6. Breast cancer in situ
  7. Dyspnoea (difficult or laboured respiration)
  8. Feeling hot
  9. Flushing (the warm, red condition of human skin)
  10. Metastases to liver (cancer spreads to liver)

60+:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Arthralgia (joint pain)
  4. Back pain
  5. Nephropathy (damage to or disease of a kidney)
  6. Obesity (having too much body fat)
  7. Pain in extremity
  8. Urinary tract infection
  9. Fatigue (feeling of tiredness)
  10. Gait disturbance

What are the existing conditions these people have? *

  1. High Blood Pressure: 28 people, 36.36%
  2. High Blood Cholesterol: 22 people, 28.57%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 20 people, 25.97%
  4. Pain: 19 people, 24.68%
  5. Indigestion: 9 people, 11.69%
  6. Stress And Anxiety: 9 people, 11.69%
  7. Fluid Retention (an abnormal accumulation of fluid in the blood): 8 people, 10.39%
  8. Asthma: 8 people, 10.39%
  9. Type 2 Diabetes: 7 people, 9.09%
  10. Depression: 5 people, 6.49%

* Approximation only. Some reports may have incomplete information.

Do you take Exforge and Novolog?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Exforge and Novolog:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Exforge:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Novolog:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Exforge and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Novolog and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate; valsartan and insulin aspart recombinant (the active ingredients of Exforge and Novolog, respectively), and Exforge and Novolog (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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