Exforge and Uloric drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Exforge (amlodipine besylate; valsartan) and Uloric (febuxostat). Common drug interactions include breast cancer among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Exforge and Uloric. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Exforge?

Exforge has active ingredients of amlodipine besylate; valsartan. It is often used in high blood pressure. eHealthMe is studying from 13,350 Exforge users. Check the latest studies of Exforge.

What is Uloric?

Uloric has active ingredients of febuxostat. It is often used in gout. eHealthMe is studying from 8,067 Uloric users. Check the latest studies of Uloric.



On Jul, 12, 2026

15 people who take Exforge and Uloric together, and have interactions are studied.

Exforge and Uloric drug interactions.

What are the common drug interactions of Exforge and Uloric, by gender? *:

female:

  1. Breast cancer
  2. Localised infection (infection at the single location)
  3. Malaise (a feeling of general discomfort or uneasiness)
  4. Nausea (feeling of having an urge to vomit)
  5. Pneumonia
  6. Renal cancer (cancer of kidney)
  7. Skin ulcer
  8. Upper respiratory tract infection
  9. Uterine cancer

male:

  1. Chronic kidney disease
  2. Skin disorder (skin disease)
  3. Drug ineffective
  4. Haemoglobin decreased
  5. Hypercholesterolaemia (high levels of cholesterol in the blood)
  6. Nausea (feeling of having an urge to vomit)
  7. Palpitations (feelings or sensations that your heart is pounding or racing)
  8. Pulmonary embolism (blockage of the main artery of the lung)
  9. Renal failure (kidney dysfunction)
  10. Vomiting

What are the common drug interactions of Exforge and Uloric, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Chronic kidney disease
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  3. Drug ineffective
  4. Nausea (feeling of having an urge to vomit)
  5. Vomiting

50-59:

n/a

60+:

  1. Skin disorder (skin disease)
  2. Breast cancer
  3. Skin ulcer
  4. Upper respiratory tract infection
  5. Uterine cancer
  6. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  7. Haemoglobin decreased
  8. Localised infection (infection at the single location)
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

  1. Diabetes: 3 people, 20.00%
  2. High Blood Cholesterol: 3 people, 20.00%
  3. Urinary Retention (the inability to completely or partially empty the bladder): 2 people, 13.33%
  4. Infection: 2 people, 13.33%
  5. Asthma: 2 people, 13.33%
  6. Constipation: 2 people, 13.33%
  7. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 13.33%
  8. Gastric Ulcer (stomach ulcer): 2 people, 13.33%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 13.33%
  10. Headache (pain in head): 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

Do you take Exforge and Uloric?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Exforge and Uloric:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Exforge:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Uloric:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Exforge and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Uloric and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate; valsartan and febuxostat (the active ingredients of Exforge and Uloric, respectively), and Exforge and Uloric (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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