Exidine and Duoneb drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Exidine (chlorhexidine gluconate) and Duoneb (albuterol sulfate; ipratropium bromide). Common drug interactions include dyspnoea among females and osteonecrosis of jaw among males.

The phase IV clinical study analyzes what interactions people have when they take Exidine and Duoneb. It is created by eHealthMe based on reports of 88 people who take the same drugs from the FDA, and is updated regularly.

What is Exidine?

Exidine has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 17,299 Exidine users. Check the latest studies of Exidine.

What is Duoneb?

Duoneb has active ingredients of albuterol sulfate; ipratropium bromide. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 8,093 Duoneb users. Check the latest studies of Duoneb.

On Aug, 11, 2026

88 people who take Exidine and Duoneb together, and have interactions are studied.

What are the common drug interactions of Exidine and Duoneb, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Subcutaneous abscess
Death
Sepsis (a severe blood infection that can lead to organ failure and death)
Tooth abscess (pus formation in tooth)
Mania (a state of abnormally elevated or irritable mood)
Pneumonia fungal
Pulmonary oedema (fluid accumulation in the lungs)
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Skin lesion

male:

Osteonecrosis of jaw (death of bone of jaw)
Nausea (feeling of having an urge to vomit)
Anxiety
Injury
Vomiting
Arteriosclerosis (thickening and hardening of arteries)
Ingrowing nail
Pain in extremity
Paronychia (infection in the tissues adjacent to a nail on a finger or toe)
Atelectasis (partial or complete collapse of the lung)

What are the common drug interactions of Exidine and Duoneb, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cardiac arrest
Haemophilus test positive
Pulseless electrical activity
Pyrexia (fever)
Respiratory failure (inadequate gas exchange by the respiratory system)
Cervical vertebral fracture
Clavicle fracture
Hyperthermia (body temperature greatly above normal)
Infusion related reaction
Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)

40-49:

Subcutaneous abscess
Abscess (pus)
Abscess limb (limb infection)
Cellulitis (infection under the skin)
Escherichia sepsis (bacterial infection by escherichia coli)
Groin abscess (pus in groin)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Perineal abscess
Perirectal abscess
Sepsis (a severe blood infection that can lead to organ failure and death)

50-59:

Hypotension (abnormally low blood pressure)
Swelling
Abdominal pain
Anaemia (lack of blood)
Anxiety
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Deafness
Depression
Diarrhoea

60+:

Pneumonia
Sepsis (a severe blood infection that can lead to organ failure and death)
Death
Hypertransaminasaemia
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypoxia (low oxygen in tissues)
Renal failure (kidney dysfunction)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tooth disorder (tooth disease)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 17 people, 19.32%
Pain: 12 people, 13.64%
Metastases To Bone (cancer spreads to bone): 10 people, 11.36%
Insomnia (sleeplessness): 7 people, 7.95%
Depression: 6 people, 6.82%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 5 people, 5.68%
Osteoporosis (bones weak and more likely to break): 5 people, 5.68%
Nausea (feeling of having an urge to vomit): 5 people, 5.68%
Constipation: 5 people, 5.68%

* Approximation only. Some reports may have incomplete information.

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