Exjade and Elavil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Exjade (deferasirox) and Elavil (amitriptyline hydrochloride). Common drug interactions include constipation among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Exjade and Elavil. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Exjade?

Exjade has active ingredients of deferasirox. It is often used in iron overload. eHealthMe is studying from 29,456 Exjade users. Check the latest studies of Exjade.

What is Elavil?

Elavil has active ingredients of amitriptyline hydrochloride. It is often used in depression. eHealthMe is studying from 20,724 Elavil users. Check the latest studies of Elavil.



On Jul, 20, 2026

40 people who take Exjade and Elavil together, and have interactions are studied.

Exjade and Elavil drug interactions.

What are the common drug interactions of Exjade and Elavil, by gender? *:

female:

  1. Constipation
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  3. Abdominal pain upper
  4. Oropharyngeal pain
  5. Pain
  6. Pharyngitis (inflammation of the pharynx, causing a sore throat)
  7. Swollen tongue (swelling of tongue)
  8. Throat irritation
  9. Throat tightness
  10. Vomiting

male:

  1. Pneumonia
  2. Diarrhoea
  3. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  4. Dizziness
  5. Nausea (feeling of having an urge to vomit)
  6. Renal cyst (kidney cyst)
  7. Renal failure acute (rapid kidney dysfunction)
  8. Vomiting
  9. Dental caries
  10. Pulmonary oedema (fluid accumulation in the lungs)

What are the common drug interactions of Exjade and Elavil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Asthma
  2. Dyskinesia (abnormality or impairment of voluntary movement)
  3. Hypoaesthesia (reduced sense of touch or sensation)
  4. Neuropathy peripheral (surface nerve damage)
  5. Tremor (trembling or shaking movements in one or more parts of your body)
  6. White blood cell count increased

20-29:

  1. Diarrhoea
  2. Abdominal pain upper
  3. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  4. Nausea (feeling of having an urge to vomit)
  5. Pain
  6. Vomiting
  7. Glaucoma (increased fluid pressure in the eye with vision loss)
  8. Haemolytic anaemia (anaemia due to haemolysis)
  9. Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
  10. Lethargy (tiredness)

30-39:

n/a

40-49:

n/a

50-59:

  1. Vision blurred

60+:

  1. Pneumonia
  2. Diarrhoea
  3. Malignant neoplasm progression (cancer tumour came back)
  4. Dental caries
  5. Tooth erosion (dissolving teeth)
  6. Urinary tract infection
  7. Spleen disorder (disease of spleen)
  8. Bone pain
  9. Death
  10. Dizziness

What are the existing conditions these people have? *

  1. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 11 people, 27.50%
  2. Anaemia Of Chronic Disease: 5 people, 12.50%
  3. Thyroid Diseases: 4 people, 10.00%
  4. Sleep Disorder: 3 people, 7.50%
  5. Pain: 3 people, 7.50%
  6. Lymphoma (cancer that begins in immune system cells): 2 people, 5.00%
  7. Cardiac Disorder: 2 people, 5.00%
  8. Breast Cancer: 2 people, 5.00%
  9. Blood Iron Increased: 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Exjade and Elavil?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Exjade and Elavil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Exjade:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Elavil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Exjade and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Elavil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on deferasirox and amitriptyline hydrochloride (the active ingredients of Exjade and Elavil, respectively), and Exjade and Elavil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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