Atrovent hfa and Simvastatin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Atrovent hfa (ipratropium bromide) and Simvastatin (simvastatin). Common drug interactions include blood pressure decreased among females and body temperature increased among males.
The phase IV clinical study analyzes what interactions people have when they take Atrovent hfa and Simvastatin. It is created by eHealthMe based on reports of 95 people who take the same drugs from the FDA, and is updated regularly.
What is Atrovent hfa?
Atrovent hfa has active ingredients of ipratropium bromide. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 2,440 Atrovent hfa users. Check the latest studies of Atrovent hfa.
What is Simvastatin?
Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,969 Simvastatin users. Check the latest studies of Simvastatin.
95 people who take Atrovent hfa and Simvastatin together, and have interactions are studied.

What are the common drug interactions of Atrovent Hfa and Simvastatin, by gender? *:
female:
- Blood pressure decreased
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Eye disorder
- Infusion related reaction
- Lethargy (tiredness)
- Logorrhoea (excessive, uncontrollable, or incoherent talkativeness)
- Malaise (a feeling of general discomfort or uneasiness)
- Memory impairment
- Oxygen consumption decreased
- Pneumonia
male:
- Body temperature increased
- Chills (felling of cold)
- Myelomalacia (softening and damage of the spinal cord due to some injury like compression by disc extrusion)
- Nausea (feeling of having an urge to vomit)
- Renal failure (kidney dysfunction)
- Spousal abuse
- Weight decreased
- Drug ineffective
- Alcohol poisoning
- Decreased appetite
What are the common drug interactions of Atrovent Hfa and Simvastatin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Drug hypersensitivity
- Influenza
- Memory impairment
- Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
- Oedema mouth (swelling of mouth)
- Pancreatitis (inflammation of pancreas)
- Swollen tongue (swelling of tongue)
40-49:
- Headache (pain in head)
- Migraine (headache)
- Cerebral infarction (less blood supply to brain resulting tissue damage)
- Cerebral vasoconstriction (constriction of brain blood vessels)
- Chronic kidney disease
- Dyspnoea (difficult or laboured respiration)
- Hyperacusis (disorder in loudness perception)
- Hypotension (abnormally low blood pressure)
- Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
- Low density lipoprotein increased (cholesterol increased in blood)
50-59:
- Impaired healing
- Insomnia (sleeplessness)
- Lacrimation increased
- Memory impairment
- Metastases to liver (cancer spreads to liver)
- Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion)
- Ocular hyperaemia (an abnormally large amount of blood in eye)
- Pancreatic neuroendocrine tumour
- Pancreatitis acute (sudden inflammation of pancreas)
- Scratch
60+:
- Nausea (feeling of having an urge to vomit)
- Dyspnoea (difficult or laboured respiration)
- Blood iron decreased
- Blood potassium increased
- Blood pressure decreased
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Eye disorder
- Infusion related reaction
- Lethargy (tiredness)
What are the existing conditions these people have? *
- High Blood Pressure: 19 people, 20.00%
- Diabetes: 13 people, 13.68%
- Pain: 12 people, 12.63%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 12.63%
- Asthma: 8 people, 8.42%
- Hypersensitivity: 7 people, 7.37%
- Depression: 7 people, 7.37%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 5.26%
- Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 5 people, 5.26%
- Cardiac Disorder: 5 people, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Atrovent hfa and Simvastatin?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Atrovent hfa (2,440 reports)
- Simvastatin (256,969 reports)
Browse all drug interactions of Atrovent hfa and Simvastatin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Atrovent hfa:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Simvastatin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Atrovent hfa and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Simvastatin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on ipratropium bromide and simvastatin (the active ingredients of Atrovent hfa and Simvastatin, respectively), and Atrovent hfa and Simvastatin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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