Extraneal and Amlodipine besylate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Extraneal (icodextrin) and Amlodipine besylate (amlodipine besylate). Common drug interactions include urinary tract infection among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Extraneal and Amlodipine besylate. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Extraneal?

Extraneal has active ingredients of icodextrin. eHealthMe is studying from 32,994 Extraneal users. Check the latest studies of Extraneal.

What is Amlodipine besylate?

Amlodipine besylate has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 75,293 Amlodipine besylate users. Check the latest studies of Amlodipine besylate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

46 people who take Extraneal and Amlodipine besylate together, and have interactions are studied.

Extraneal and Amlodipine besylate drug interactions.

What are the common drug interactions of Extraneal and Amlodipine Besylate, by gender? *:

female:

Urinary tract infection
Oedema peripheral (superficial swelling)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Anaemia (lack of blood)
Blood cholesterol decreased
Blood phosphorus decreased
Blood triglycerides decreased
Cardiac failure congestive
Death
Gangrene (body tissue dies)

male:

Pyrexia (fever)
Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
Sclerosing encapsulating peritonitis (thick peritoneal membranes)
Agitation (state of anxiety or nervous excitement)
Angioedema (rapid swelling of the dermis)
Anuria (failure of the kidneys to produce urine)
Arthralgia (joint pain)
Blood albumin decreased
Blood pressure fluctuation
Candidiasis (candidiasis or thrush is a fungal infection)

What are the common drug interactions of Extraneal and Amlodipine Besylate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anuria (failure of the kidneys to produce urine)
Fluid overload (too much fluid in the blood)
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
Peritoneal dialysis complication
Peritonitis sclerosing (rare form of peritoneal inflammation)
Ascites (accumulation of fluid in the abdominal cavity)
Haemoglobin decreased
Hepatomegaly (abnormal enlargement of the liver)
Peritoneal fibrosis (extra fibrous tissue forms in the area behind the stomach and intestines)
Subileus

30-39:

Agitation (state of anxiety or nervous excitement)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Candidiasis (candidiasis or thrush is a fungal infection)
Delirium (wild excitement)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Enterobacter infection (infection caused by bacteria of the family enterobacteriaceae)
Escherichia sepsis (bacterial infection by escherichia coli)
Fluid overload (too much fluid in the blood)
Klebsiella infection
Pneumonia

40-49:

Angioedema (rapid swelling of the dermis)
Arthralgia (joint pain)
Blood pressure fluctuation
Burning sensation
Chest pain
Dizziness
Drug hypersensitivity
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Flushing (the warm, red condition of human skin)

50-59:

Anaemia (lack of blood)
Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
Sclerosing encapsulating peritonitis (thick peritoneal membranes)
Blood albumin decreased
Gangrene (body tissue dies)
Haematocrit decreased
Haemoglobin decreased
Intestinal functional disorder
Oral intake reduced
Pyrexia (fever)

60+:

Drug hypersensitivity
Hypotension (abnormally low blood pressure)
Urinary tract infection
Pleural effusion (water on the lungs)
Blood cholesterol decreased
Blood phosphorus decreased
Blood triglycerides decreased
Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
Decreased appetite
Hypophagia (reduced food intake)

What are the existing conditions these people have? *

Chronic Renal Failure (kidney failure): 21 people, 45.65%

* Approximation only. Some reports may have incomplete information.

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