Eylea and Benicar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Eylea (aflibercept) and Benicar (olmesartan medoxomil). Common drug interactions include eyelid disorder among females and eye irritation among males.

The phase IV clinical study analyzes what interactions people have when they take Eylea and Benicar. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Eylea?

Eylea has active ingredients of aflibercept. It is often used in macular degeneration. eHealthMe is studying from 27,868 Eylea users. Check the latest studies of Eylea.

What is Benicar?

Benicar has active ingredients of olmesartan medoxomil. It is often used in high blood pressure. eHealthMe is studying from 36,002 Benicar users. Check the latest studies of Benicar.

On Jul, 11, 2026

31 people who take Eylea and Benicar together, and have interactions are studied.

What are the common drug interactions of Eylea and Benicar, by gender? *:

female:

Eyelid disorder
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Iritis (painful inflammation of the iris of the eye)
Pain
Psoriasis (immune-mediated disease that affects the skin)
Rash
Retinal haemorrhage (bleeding from retina)
Vitreous floaters (spots before the eyes)
Vitritis (inflammation of the vitreous humour of the eye)
Blindness unilateral

male:

Eye irritation
Ocular hyperaemia (an abnormally large amount of blood in eye)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Death

What are the common drug interactions of Eylea and Benicar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Death

50-59:

n/a

60+:

Blindness unilateral
Endophthalmitis (inflammation of the internal coats of the eye)
Anterior chamber flare (flare in the anterior chamber)
Eye inflammation
Iritis (painful inflammation of the iris of the eye)
Vitreous floaters (spots before the eyes)
Vitritis (inflammation of the vitreous humour of the eye)

What are the existing conditions these people have? *

Age-Related Macular Degeneration: 5 people, 16.13%
Retinal Vessel Occlusion (a blockage in one of the small arteries): 4 people, 12.90%
Choroidal Neovascularisation (creation of new blood vessels in vascular layer of eye): 4 people, 12.90%
Diabetic Retinopathy (damage to the retina caused by complications of diabetes): 3 people, 9.68%
Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 3 people, 9.68%
Renal Disorder (kidney disease): 2 people, 6.45%
Prostatic Disorder: 2 people, 6.45%
Parkinson's Disease: 2 people, 6.45%
Macular Oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken): 2 people, 6.45%
Blood Cholesterol Decreased: 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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