Eylea and Klonopin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Eylea (aflibercept) and Klonopin (clonazepam). Common drug interactions include injection site haemorrhage among females and eye irritation among males.

The phase IV clinical study analyzes what interactions people have when they take Eylea and Klonopin. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Eylea?

Eylea has active ingredients of aflibercept. It is often used in macular degeneration. eHealthMe is studying from 27,868 Eylea users. Check the latest studies of Eylea.

What is Klonopin?

Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 65,112 Klonopin users. Check the latest studies of Klonopin.

On Jul, 18, 2026

16 people who take Eylea and Klonopin together, and have interactions are studied.

What are the common drug interactions of Eylea and Klonopin, by gender? *:

female:

Injection site haemorrhage (bleeding from injection site)
Injection site pain
Nystagmus (a condition of involuntary eye movement)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Visual impairment
Vitreous floaters (spots before the eyes)
Blindness unilateral
Drug ineffective
Eye disorder

male:

Eye irritation
Ocular hyperaemia (an abnormally large amount of blood in eye)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac disorder
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Pneumonia

What are the common drug interactions of Eylea and Klonopin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Blindness unilateral
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Eye disorder
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))

What are the existing conditions these people have? *

Age-Related Macular Degeneration: 2 people, 12.50%
Renal Disorder (kidney disease): 2 people, 12.50%
Prostatic Disorder: 2 people, 12.50%
Parkinson's Disease: 2 people, 12.50%
Blood Cholesterol Decreased: 2 people, 12.50%
Choroidal Neovascularisation (creation of new blood vessels in vascular layer of eye): 2 people, 12.50%
Insomnia (sleeplessness): 2 people, 12.50%
Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 1 person, 6.25%
Back Pain: 1 person, 6.25%
Cardiac Failure Congestive: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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