Prednisolone and Naltrexone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prednisolone (prednisolone) and Naltrexone (naltrexone). Common drug interactions include drug ineffective among females and device dislocation among males.

The phase IV clinical study analyzes what interactions people have when they take Prednisolone and Naltrexone. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Prednisolone?

Prednisolone has active ingredients of prednisolone. It is often used in rheumatoid arthritis. eHealthMe is studying from 212,675 Prednisolone users. Check the latest studies of Prednisolone.

What is Naltrexone?

Naltrexone has active ingredients of naltrexone. eHealthMe is studying from 4,833 Naltrexone users. Check the latest studies of Naltrexone.



On Jul, 18, 2026

23 people who take Prednisolone and Naltrexone together, and have interactions are studied.

Prednisolone and Naltrexone drug interactions.

What are the common drug interactions of Prednisolone and Naltrexone, by gender? *:

female:

  1. Drug ineffective
  2. Pruritus (severe itching of the skin)
  3. Affective disorder (mental disorder)
  4. Anxiety
  5. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  6. Insomnia (sleeplessness)
  7. Rash pruritic (redness with itching)
  8. Urticaria (rash of round, red welts on the skin that itch intensely)
  9. Intraductal papillary mucinous neoplasm (tumour (neoplasm) that grows within the pancreatic ducts)
  10. Skin disorder (skin disease)

male:

  1. Device dislocation
  2. Umbilical hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button)
  3. Rash pruritic (redness with itching)
  4. Uveitis (inflammation of the uvea)
  5. Weight gain poor
  6. Abdominal distension
  7. Abdominal pain
  8. Drug dependence
  9. Overdose
  10. Drug ineffective

What are the common drug interactions of Prednisolone and Naltrexone, by age (0-1 to 60+)? *:

0-1:

  1. Drug ineffective

2-9:

  1. Device dislocation
  2. Umbilical hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button)
  3. Weight gain poor

10-19:

  1. Abdominal distension
  2. Abdominal pain

20-29:

  1. Affective disorder (mental disorder)
  2. Anxiety
  3. Drug ineffective
  4. Insomnia (sleeplessness)

30-39:

n/a

40-49:

  1. Acute generalised exanthematous pustulosis (acute febrile drug eruption)
  2. Dermatitis allergic (inflammation of the skin due allergic reaction)
  3. Pustular psoriasis (raised bumps on the skin that are filled with pus)
  4. Type iv hypersensitivity reaction (delayed type hypersensitivity as the reaction takes two to three days to develop)

50-59:

  1. Gastritis fungal (inflammation of stomach caused by fungal infection)
  2. Respiratory failure (inadequate gas exchange by the respiratory system)
  3. Respiratory tract infection
  4. Viral infection

60+:

  1. Pruritus (severe itching of the skin)
  2. Rash pruritic (redness with itching)
  3. Otorrhoea (discharge from the ear)
  4. Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
  5. Thrombosis (formation of a blood clot inside a blood vessel)
  6. Visual impairment
  7. Drug ineffective
  8. Erythema (redness of the skin)
  9. Insomnia (sleeplessness)
  10. Rash

What are the existing conditions these people have? *

  1. Pain: 5 people, 21.74%
  2. Dyskinesia (abnormality or impairment of voluntary movement): 5 people, 21.74%
  3. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 4 people, 17.39%
  4. Respiratory Disorder (respiratory disease): 4 people, 17.39%
  5. Neurodermatitis (a skin disorder characterized by long lasting itching and scratching): 4 people, 17.39%
  6. Nervous System Disorder (a general class of medical conditions affecting the nervous system): 4 people, 17.39%
  7. Abdominal Pain: 3 people, 13.04%
  8. Thrombosis (formation of a blood clot inside a blood vessel): 3 people, 13.04%
  9. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 3 people, 13.04%
  10. Parkinson's Disease: 3 people, 13.04%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Prednisolone and Naltrexone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prednisolone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Naltrexone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prednisolone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Naltrexone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on prednisolone and naltrexone (the active ingredients of Prednisolone and Naltrexone, respectively), and Prednisolone and Naltrexone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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