Eylea and Vitamin d3 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Eylea (aflibercept) and Vitamin d3 (cholecalciferol). Common drug interactions include visual impairment among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Eylea and Vitamin d3. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Eylea?

Eylea has active ingredients of aflibercept. It is often used in macular degeneration. eHealthMe is studying from 27,868 Eylea users. Check the latest studies of Eylea.

What is Vitamin d3?

Vitamin d3 has active ingredients of cholecalciferol. It is often used in heart health. eHealthMe is studying from 32,171 Vitamin d3 users. Check the latest studies of Vitamin d3.

On Jul, 17, 2026

40 people who take Eylea and Vitamin d3 together, and have interactions are studied.

What are the common drug interactions of Eylea and Vitamin D3, by gender? *:

female:

Visual impairment
Blindness
Blindness transient (sudden loss of vision)
Eye inflammation
Muscle spasms (muscle contraction)
Anterior chamber inflammation
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Blindness unilateral
Blood pressure increased

male:

Death
Visual acuity reduced (reduced clearness of vision)
Uveitis (inflammation of the uvea)
Blindness
Choroidal neovascularisation (creation of new blood vessels in vascular layer of eye)
Choroiditis (infection of vascular layer of eye)
Drug ineffective
Eye disorder
Eye pain
Ocular hyperaemia (an abnormally large amount of blood in eye)

What are the common drug interactions of Eylea and Vitamin D3, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Blindness
Visual impairment
Blindness unilateral
Blood pressure increased
Cardiac failure
Carotid artery occlusion (artery blockage)
Chest discomfort
Choroidal neovascularisation (creation of new blood vessels in vascular layer of eye)
Choroiditis (infection of vascular layer of eye)
Dry mouth

What are the existing conditions these people have? *

Age-Related Macular Degeneration: 5 people, 12.50%
Retinal Vessel Occlusion (a blockage in one of the small arteries): 4 people, 10.00%
Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 3 people, 7.50%
Choroidal Neovascularisation (creation of new blood vessels in vascular layer of eye): 3 people, 7.50%
Macular Oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken): 2 people, 5.00%
Diabetic Retinopathy (damage to the retina caused by complications of diabetes): 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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