Ezetimibe and Afinitor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ezetimibe (ezetimibe) and Afinitor (everolimus). Common drug interactions include pericardial effusion among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Ezetimibe and Afinitor. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Ezetimibe?

Ezetimibe has active ingredients of ezetimibe. It is often used in high blood cholesterol. eHealthMe is studying from 30,849 Ezetimibe users. Check the latest studies of Ezetimibe.

What is Afinitor?

Afinitor has active ingredients of everolimus. It is often used in breast cancer metastatic. eHealthMe is studying from 41,680 Afinitor users. Check the latest studies of Afinitor.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

28 people who take Ezetimibe and Afinitor together, and have interactions are studied.

Ezetimibe and Afinitor drug interactions.

What are the common drug interactions of Ezetimibe and Afinitor, by gender? *:

female:

Pericardial effusion (fluid around the heart)
Renal haematoma (blood collection in kidney)
Urinary tract infection
Weight decreased
Blood glucose increased
Blood creatinine increased
Malaise (a feeling of general discomfort or uneasiness)
Pyrexia (fever)
Diarrhoea
Glomerular filtration rate increased

male:

Diarrhoea
Nausea (feeling of having an urge to vomit)
Stomatitis (inflammation of mucous membrane of mouth)
Abdominal discomfort
Abdominal distension
Abdominal pain
Abdominal pain upper
Back pain
Blood pressure increased
Carcinoid tumour (slow growing tumour)

What are the common drug interactions of Ezetimibe and Afinitor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Abdominal pain
Blood creatinine increased
Blood glucose increased
Bone disorder
Drug ineffective
Glomerular filtration rate increased
Haemoglobin decreased
Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
Jaw fracture
Mean cell haemoglobin decreased (less than normal haemoglobin per red blood cell in a sample of blood)

60+:

Diarrhoea
Malaise (a feeling of general discomfort or uneasiness)
Headache (pain in head)
Ketoacidosis (high concentrations of ketone bodies in blood)
Nausea (feeling of having an urge to vomit)
Oral candidiasis (fungal infection of mouth)
Pleural effusion (water on the lungs)
Pneumonia
Sinusitis (inflammation of sinus)
Swelling

What are the existing conditions these people have? *

Renal Cell Carcinoma (a kidney cancer): 9 people, 32.14%
Diabetes: 6 people, 21.43%
Metastases To Bone (cancer spreads to bone): 4 people, 14.29%
High Blood Pressure: 4 people, 14.29%
Pancreatic Neuroendocrine Tumor: 3 people, 10.71%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 10.71%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 3 people, 10.71%
Breast Cancer: 3 people, 10.71%
Dyslipidaemia (abnormal amount of lipids): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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