Fanapt and Clonidine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fanapt (iloperidone) and Clonidine (clonidine). Common drug interactions include tardive dyskinesia among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Fanapt and Clonidine. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Fanapt?

Fanapt has active ingredients of iloperidone. It is often used in schizophrenia. eHealthMe is studying from 1,443 Fanapt users. Check the latest studies of Fanapt.

What is Clonidine?

Clonidine has active ingredients of clonidine. It is often used in high blood pressure. eHealthMe is studying from 65,644 Clonidine users. Check the latest studies of Clonidine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

16 people who take Fanapt and Clonidine together, and have interactions are studied.

What are the common drug interactions of Fanapt and Clonidine, by gender? *:

female:

Tardive dyskinesia (a disorder that involves involuntary movements)
Abnormal behaviour
Blood prolactin increased
Delusional perception (delusional perception describes, confusingly, a true perception, to which a patient attributes a false meaning)
Diarrhoea
Drug ineffective
Gastric disorder (disease of stomach)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Heart rate increased
Injury

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Death
Priapism (prolonged and painful erection that can last from several hours up to a few days)
Diarrhoea
Rash pruritic (redness with itching)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tremor (trembling or shaking movements in one or more parts of your body)

What are the common drug interactions of Fanapt and Clonidine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Tardive dyskinesia (a disorder that involves involuntary movements)
Diarrhoea
Rash pruritic (redness with itching)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tremor (trembling or shaking movements in one or more parts of your body)

20-29:

Diarrhoea
Drug ineffective
Gastric disorder (disease of stomach)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Heart rate increased
Loss of consciousness
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Death

30-39:

Abnormal behaviour
Chronic kidney disease
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

50-59:

n/a

60+:

Priapism (prolonged and painful erection that can last from several hours up to a few days)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 18.75%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 3 people, 18.75%
Depression: 2 people, 12.50%
Affective Disorder (mental disorder): 2 people, 12.50%
Bipolar Disorder (mood disorder): 2 people, 12.50%
Stress And Anxiety: 2 people, 12.50%
Pain: 1 person, 6.25%
Cough: 1 person, 6.25%
Sleep Disorder: 1 person, 6.25%
Sinusitis (inflammation of sinus): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Fanapt and Clonidine?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously